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《ZOOLOGICAL RESEARCH》 1998-06
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THE MOLECULAR BIOLOGY OF THE BIOLOGICAL CLOCK GENE, period

ZHENG Xiang zhong ①② ZHANG Ya ping ① ZHU Ding liang ② GENG Zhen cheng ② (① Lab of Cellular and Molecular Evolution,Kunming Institute of Zoology, the Chinese Academy of Sciences,Kunming 650223) (② Institute of Genetics,Fuda  
Many biochemical,physiological and behavioural processes in organisms ranging from microorganisms to vertebrates exhibit circadian rhythms driven by endogenous oscillators.Since the cloning of the biological clock gene period in Drosophila ,the endeavor in two decades to understand the molecular components that constitute these oscillators has been rewarded:we now know the circadian rhythm is driven by four cogs:PER,TIM,CLOCK and BMAL1,and the mechanism which govern the circadian oscillation has been elucidated.This work on biological clock genes is spectacular not only for its heuristic value,but also because it illustrate the synegistic power of genetics and genomics.Given the evolutionary conservation of the mechanisms that govern the fundermental biological processes,the period story will greatly accelerate the reseach progress on human complex behavior
【Fund】: 国家自然科学基金 中国科学院昆明动物研究所细胞与分子进化开放研究实验室资助
【CateGory Index】: Q71,Q753
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【References】
Chinese Journal Full-text Database 1 Hits
1 LIU Zong Min ZHANG Ya Ping ① (Laboratory of Cellular and Molecular Evolution,Kunming Institute of Zoology,the Chinese Academy of Sciences,Kunming 650223,China);Timeless Gene and Biological Clock Genes[J];Zoological Research;2001-06
【Co-references】
Chinese Journal Full-text Database 10 Hits
1 LAN HONG SHI LI-MING (Laboratory off Cellular and Molecular Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, China);THE MITOCHONDRIAL DNA EVOLUTION OF FOUR SPECIES OF CANIDAE[J];Acta Zoologica Sinica;1996-01
2 LI Ming WANG Xiao Ming SHENG He Lin (Department of Biology,East China Normal University,Shanghai 200062, China);MITOCHONDRIAL DNA DIVERGENCE AND PHYLOGENY OF FOUR SPECIES OF DEER OF THE GENUS CERVUS[J];ACTA ZOOLOGICA SINICA;1999-01
3 TAN YuanDe (Life Science College,Hunan Normal University,Changsha 410081,China);A NEW METHOD FOR RECONSTRUCTION OF PHYLOGENETIC TREE:TRIAL ERROR METHOD[J];Acta Zoologica Sinica;2000-04
4 Guang XU FANG Qing-Quan ** James. E. KEIRANS Lance. A. DURDEN (Department of Biology and the U.S. National Tick Collection, Georgia Southern University, Statesboro, GA, 30460-8042);Application of Bayesian method for inferring phylogenetic relationships of ticks within the genus Ixodes[J];Acta Zoologica Sinica;2003-03
5 SHA Zhong-Li 1,2,ZHU Chao-Dong1,Robert W.MURPHY3,HUANG Da-Wei 1,5,Stephen G.COMPTON41.Institute of Zoology,Chinese Academy of Sciences,Beijing 100080,China2.Graduate School of the Chinese Academy of Sciences, Beijing 100039,China3.Centre for Biodiversity and Conservation Biology,Royal Ontario Museum,100 Queens Park,Toronto,Ontario,M5S 2C6,Canada4.Centre for Biodiversity and Conservation,School of Biology,University of Leeds,Leeds,LS2 9JT,United Kingdom5.Plant Protection College,Shandong Agricultural University,Taian,Shandong 271018,China;A molecular phylogeny of eulophid wasps inferred from partial 18S gene sequences[J];Acta Zoologica Sinica;2006-02
6 SUN Zheng-Li,JIANG Guo-Fang ,HUO Guang-Ming,LIU Dian-FengCollege of Life Sciences,Nanjing Normal University,Nanjing 210097,China;A phylogenetic analysis of six genera of Acrididae and monophyly of Acrididae in China using 16S rDNA sequences(Orthoptera,Acridoidea)[J];Acta Zoologica Sinica;2006-02
7 CHEN Na,ZHU Guo-Ping,HAO Jia-Sheng **,ZHANG Xiao-Ping,SU Cheng-Yong,PAN Hong-Chun,WU Dong-XiaLaboratory of Molecular Evolution and Biodiveristy,College of Life Sciences,Anhui Normal University,Wuhu 241000,Anhui Province;Molecular phylogenetic analysis of the main lineages of Nymphalidae(Lepidoptera,Rhopalocera)based on mitochondrial 16S rDNA sequences[J];Acta Zoologica Sinica;2007-01
8 SHAO Hong Guang( Shanghai Institute of Entomology,Chinese Academy of Sciences,Shanghai 200025);SOME MOLECULAR EVIDENCES FOR SYSTEMATIC AND EVOLUTIONARY PROBLEMS IN ARTHROPODA[J];ACTA ZOOTAXONOMICA SINICA;2000-01
9 CHENG Xin Yue ZHOU Hong Zhang ZHANG Guang Xue( Institute of Zoology, Chinese Academy of Sciences, Beijing 100080 );PERSPECTIVE OF MOLECULAR BIOLOGICAL TECHNIQUES APPLIED IN INSECT SYSTEMATICS[J];ACTA ZOOTAXONOMICA SINICA;2000-02
10 LIU Dian-Feng, JIANG Guo-FangInstitute of Genetic Resources, College of Life Sciences, Nanjing Normal University, Nanjing 210097, China;THE APPLICATION OF NUCLEAR GENES SEQUENCES IN INSECT MOLECULAR SYSTEMATICS[J];Acta Zootaxonomica Sinica;2005-03
【Secondary References】
Chinese Journal Full-text Database 3 Hits
1 ZHAO Hao-qin et al(Jiangsu University of Science and Technology,Zhenjiang,Jiangsu 212003 );Cloning and Sequence Analysis of Biological Clock Gene Bmtim2 in Bombyx mori L.[J];Journal of Anhui Agricultural Sciences;2008-17
2 SONG Yan ZHU Xiao-Su XU Li XU Shi-Qing(Department of Applied Biology,School of Basic Medicine & Biological Science,Soochow University,Suzhou Jiangsu 215123,China);The Molecular Mechanism of Inset Circadian Clock Entrained by Light and Temperature[J];Science of Sericulture;2009-02
3 ZHANG Jia-wei1,RAN Xue-qin1,WANG Jia-fu1,2(1.Faculty of Animal Science,Guizhou University,Guizhou Guiyang 550025,China;2.Guizhou Key Laboratory of Agricultural Bioengineering,Guizhou Guiyang 550025,China);Genetic Diversity of Mitochondrial DNA Sequences in Xiasi Dog[J];Journal of Mountain Agriculture and Biology;2009-02
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