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《Chinese Journal of Animal Nutrition》 2010-03
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Effects of Chitosan on Immune Function of Aquatic Animals and Its Possible Regulation Mechanism

XIAO Weiwei1,2 FENG Lin1,2 LIU Yang1,2 JIANG Jun1,2 LI Shuhong1,2 ZHOU Xiaoqiu1,2(1. Animal Nutrition Institute,Sichuan Agricultural University,Ya’an 625014,China; 2. Key Laboratory for Animal Disease-resistance Nutrition of China Minstry of Education,Ya’an 625014,China)  
It was found that chitosan could improve the non-specific immune function of aquatic animals through enhancing the activities of antimicrophyte enzymes and the phagocytosis ability of phagocyte. Chitosan could also promote the production of antibody,thus improved the specific immune function of aquatic animals. However,there were few studies on its regulation mechanism in the aquatic animals. The studies in the terrestrial animals field indicated that the improvement of immune function by adding chitosan might result mainly from regulating the NO and PGE2 production in immune cells.
【Fund】: 四川省教育厅重点项目(07ZA068)
【CateGory Index】: S963
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