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《Chinese Journal of Control of Endemic Disease》 1995-05
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STUDY ON LIP ID PEROXIDATION IN RAT LIVER CAUSED BY FLUORIDE AND THE ANTAGONISM OF SELENIUM

Yang Chengfeng,et al Department of Environmental Health ,Tong ji Medical University ,Wuhan  
The lipid peroxidation in rat liver caused by fluoride and the antagonism of selenium was studied by adding fluoride(50mg/Dor/and selenium(0. 5mg/L)to drinking water. The results showed that adding fluoride to drinking water could significantly increase the contents of free radical, lipid peroxide (LPO ), and decrease the content of glutathione(GSH)and the activity of glutathione peroxidase(6SH-Px)in rat liver. The lipid peroxidation in rat liver caused by fluoride could be antagonized by adding selenium to drinking water simultaneously. But the decrease of activity of liver GSH-Px caused by fluoride was not affected obviously by adding selenium to drinking water.
【CateGory Index】: R363
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