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《Journal of First Military Medical University》 2004-11
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Expression of macrophage migration inhibition factor in pancreatic carcinoma tissue

JIN Zhi-qing, ZHI Fa-chao, CHEN Xue-qing, WANG Ya-dongInstitute for Digestive Disease of PLA, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China  
Objective To observe the expression of macrophage migration inhibitory factor (MIF) in pancreatic carcinoma tissue and analyze the relationship between MIF expression and clinical manifestations. Methods MIF expression in pancreatic carcinoma and normal pancreatic tissue were detected with immunohistochemical method. Result The positivity rates of MIF in pancreatic carcinoma and normal pancreatic tissue were 69.4%(25/36) and 0(0/10) respectively. MIF expression was found to relate to the degree of cell differentiation of pancreatic carcinoma, but not to the clinical stages or the status of lymph node metastasis. Conclusion MIF might be related to the pathogenesis of pancreatic carcinoma.
【CateGory Index】: R735.9
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