Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Journal of Southern Medical University》 2007-12
Add to Favorite Get Latest Update

Influence of chronic HBV infection in the husband on the outcome of IVF-ET treatment

ZHAO Er-yong1, CHEN Shi-ling1, SUN Ling1, YIN Min-na1, XIONG Xia-si1, SONG Juan1, SONG Ya-nan2, ZHOU Yuan-ping2 1Center for Reproductive Medicine, 2Department of Infectious Diseases, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China  
Objective To investigate the outcome of in vitro fertilization and embryo transfer (IVF-ET) in couples with the husband positive for chronic infection of hepatitis B virus (HBV). Methods This study involved 102 infertile couples receiving IVF-ET with the husbands(but not the wives) positive for hepatitis B surface antigen (HBsAg), and another 204 couples negative for HBsAg receiving the treatment served as the control group. The cumulative embryo score, fertilization rate, cleavage rate, rate of good quality embryos, implantation rate, clinical pregnancy rate, first trimester and late miscarriage rates, delivery rate, and neonatal malformation rate were recorded and compared between the two groups. Results Between the HBsAg-positive and the control groups, the cumulative embryo score (52.8±18.7 vs 55.4±16.9), insemination rate (66.9% vs 66.1%), cleavage rate (97.6% vs 97.2%), rate of good quality embryos (34.0% vs 37.1%), implantation rate (40.9% vs 34.6%), clinical pregnancy rate (56.9% vs 50%), first trimester miscarriage rate (6.9% vs 5.9%) and late pregnancy miscarriage rate (8.6% vs 4.9%), delivery rate (40.2% vs 43.6%) and neonatal malformation rate (0 vs 0) were all similar (P0.05). Conclusion Chronic HBV infection in the husband might not affect the outcome of IVF-ET treatment.
【Fund】: 国家973重大科学研究计划(2007CB948104);; 国家自然科学基金(30671872)~~
【CateGory Index】: R714.8
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved