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《Progress In Veterinary Medicine》 2001-02
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Effect of Epimedium Propolis Adjuvant on Natural Killer Lymphocyte Activity

LIU Jia guo,HU Yuan liang,ZHANG Bao kang,SON Da lu,BU Zhi liang (Veterinary Medicine College,Nanjing Agric.Uni,Nanjing 210095,China)  
The effect of Epimedium Propolis adjuvant on the NK cell activity of mousy splenic and chicken’s peripheral blood was tested respectively by microassay LDH release.The results were as follows:The NK cell activity of mousy splenic decreased with the sequence as follows:group Ⅰ (treated by EPA only) group Ⅳ (treated with physidogical saline solution),group Ⅱ (treated by EPA with Cyclophosphamidum),group Ⅲ (treated with Cyelophosphamidum only).The difference among these group atoresaid was remarkable( P 0.05 or P 0.01) but between the group Ⅱ and Ⅳ no significant( P 0.05).The difference in the 4 week old mice was superior to that in the 8 week old mice.The NK cell activity of chicken in those groups treated with EPA was significantly superior to those treated by physiological saline only on the 35th day and ,moreover,the activity in those treated by 0.4ml EPA was higher than those by 0.2ml EPA( P 0.05).These results indicated that the EPA could not only enhance the NK cell activity of experimental animals,but also resist the immunosuppression by the Cyelophosphamidum,especially to the juvenile animal.And there was some kinds of relation between the effect and the dosage of the EPA.
【Fund】: 国家自然科学基金资助项目! (392 70 5 2 2 )
【CateGory Index】: S853.7
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