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《Progress In Veterinary Medicine》 2003-03
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Genetic and Mutation Analysis of Porcine Reproductive and Respiratory Syndrom Virus Genome

SHI Xi ju,HAN Chun lai,XIA Chun,WANG Ming (College of Veterinary Medcine,China Agricultural University,Beijing ,100094,China)  
Porcine reproductive and respiratory syndrom(PRRS),characterized by severe reproductive failure in sows and respiratory disease in young pigs,was first recognized in the late 1980s .Since its appearance,PRRS has devastated the wordwide swine industry with tremendous economic losses,causing abortion ,stillbirth and high mortality in pregnant swines.Due to its complexities of pathogeny and immune mechanism,PRRS was widely studied,but the effective prevention strategies were not known.So it is necessary to study its genomic genetics and mutation.In this article,the genetic and mutation of PRRSV genome, including 5′UTR,ORF1,constitutive protein gene,3′UTR were analyzed to provide some new ideas for controling effectively this disease.
【CateGory Index】: S858.28
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