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《Progress in Veterinary Medicine》 2006-09
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Analysis of Immunodeficiency in an Old Macaca fascicularis

MIN Fan-gui,WU Yu-e,LI Wen-de,PAN Jin-chun,LIU Zhong-hua,HUANG Ren(Guangdong Laboratory Animals Monitoring Institute,Guangzhou,Guangdong,510260,China)  
To observe the changes of the immunity system of an old Macaca fascicularis,we measured the numerical value of CD4 and CD8 in blood by flow cytometer and observed the clinical signs and pathologic changes of spleen,thymus,lymph nodes and so on.The CD4/CD8 showed converted and the thymus disappeared.There was no germinal center in the spleen and lymph nodes.It proved that the old monkey was in typical immunodeficiency.
【Fund】: 广东省重点科技攻关项目(2003C60101)
【CateGory Index】: R-332
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