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《Progress in Veterinary Medicine》 2007-07
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Advance in Brucellosis

TUERHONG Nu-er1,GU Wen-xi1,HE Qian-ni1,Rehemujiang2,BUHILIQIEMU Yiganbadi3,LIU Li-ya1(1.Veterinary Institute,Xinjiang Academy of Animal Sciences,Urumqi,Xinjiang,830000,China;2.Xinjiang Animal Epidemic Prevention And Monitoring Station,Urumqi,Xinjiang,830063,China;3.Livestock Bureau of Kashgar City,Kashgar,Xinjiang,844000,China)  
Brucellosis is kind of most worldwide prevailed harmful zoonosis at present.It exists and spreads in more than 170 countries in the world and 25 provinces of our country.With the rapid development of animal husbandry,the Brucellosis is obviously getting more serious in most of the epidemic area.In 2005,19664 people were affected by the disease in whole country,the incidence of the disease was 1.504/100000,exceeded the historical highest number.Brucella is a kind of gram negative bacterium which parasitizes in the cell.It mainly causes the undulant fever and chronic infection of human being,the orchitis and abortion of animals,directly harming the public security and bringing a serious economic loss.Recent years,the brucella was separated from the body of many oceanic mammals such as seals,dolphins and whales.Through the method of DNA same source comparison,it was found out that the oceanic and land mammals burcella had 90% of source similarities.With the development of molecular biology,the study on the molecular structure of burcella had got a lot of new discoveries continuously.This provided more probabilities for understanding and controlling of brucellosis.This paper reviewed in detail on the progress in the study of Brucellosis,including current and historical situation of Brucellosis epidemic,the molecular character of antigen,the methods of detection and the vaccination in Brucellosis.
【Fund】: 新疆维吾尔自治区自然科学基金项目(200321115)
【CateGory Index】: S855
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