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《Progress in Veterinary Medicine》 2008-07
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Study on the Machanisms of EMX in Inhibiting Side Effects of 6-MP in Mice

GUO Zhi-hong(Qinghai Academy of Animal Husbandry and Veterinary Medicine,Xining,Qinghai,810016,China)  
40 five-week-old DDY mice were divided into 4 groups,they were control group,6-MP group,6-MP and 500 diluted drinking EMX group,6-MP and injecting EMX group,respectively.During experimental period,the weights of mice were obtained in the special time.After 8 weeks of experiment,the mice were killed,the coefficients of thymus and spleen,the amount of bone marrow DNA,the contents of peroxid lipids in the liver were detected.The results showed that 6-MP caused the deplumations,lose weights,the decreasing of coefficients of thymus and spleen,the damage liver and other side effects,while the EMX had effects on inhibiting the side effects which were caused by the 6-MP,an anticancer medicine,and on enhancing immunocompetent.
【CateGory Index】： R285
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