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《Progress in Veterinary Medicine》 2013-08
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Effects of Poplar Flower Water Extract on Immune Function in Immunosuppressed Mice

LI li 1,LIU Zhe 2(1.College of Animal Husbandry and Veterinary,Liaoning Medical University Medicine,Jinzhou,Liaoning,121001,China;2.Xingcheng Sijia Animals Health Supervision Institute,Xingcheng,Liaoning,125000,China)  
To study the effects of poplar flower water extract(PWE)on immune modulation in immunosuppressed mice,three hundred mice were allocated to control group,cyclophosphamide(CY)model group,treatment groupⅠ(CY+0.1mg/kg.d),treatment groupⅡ(CY+0.2mg/kg.d)and treatment groupⅢ(CY+0.4mg/kg.d),mice in control group and CY model group were orally administered with sterile water.after 30days,changes on immune function in immunosuppressed mice were detected.The results showed that treatment groupⅠcan improce distinctly proliferation ability,delayed type hypersensitivity reaction,phagocytic percentage,phagocytic index,the clearance rate of charcoal particles and NK cell activity.Treatment groupⅡ,Ⅲ can enhance remarkablely immune organs indexes,the number of hemolytic plaque and the level of serum hemolysin,very significantly improve proliferation ability,delayed type hypersensitivity reaction,phagocytic percentage,phagocytic index,the clearance rate of charcoal particles and NK cell activity.These results explained that PWE can reverse immune suppression and has effect on improving immune function in mice.
【CateGory Index】: S853.7
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