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《Progress in Veterinary Medicine》 2014-02
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Progress on Extraction Technology and Detecting Methods of Swainsonine

HAO Bao-cheng;YANG Xian-peng;HU Yong-hao;LIANG Jian-ping;Key Laboratory of New Animal Drug Project,Gansu province/Key Laboratory of Veterinary Pharmaceutics Discovery,Ministry of Agricultural/Lanzhou Institute of Husbandry and Pharmaceutical Sciences of CAAS;College of Veterinary Medicine,Gansu Agricultural University;  
Locoweed,known as poisonous Astragalus and Oxytropis genera,is the most serious hazard class of poisonous weeds in the world,it showed higher hazards in pastoral areas.Also,swainsonine can improve the inhibitory effects of interferon on the cell,and it shows great application potential.Research progress on the extraction technology and detecting methods of swainsonine were summarized.The methods for qualitative and quantitative detection of swainsonine,including thin layer chromatography(TLC),gas chromatography(GC),high performance liquid chromatography(HPLC),and enzyme analysis,were discussed,and the advantages and disadvantages of these methods were also compared to each other.
【Fund】: 国家高新技术研究发展计划(863计划)(2011AA10A214);; 中央级公益性科研院所基本科研业务费专项资金(1610322012001);; 西藏横向委托项目(2011-2013)
【CateGory Index】: TQ914.1
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