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《Progress in Veterinary Medicine》 2014-08
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Pharmacokinetics and Residue Detection of Avermectin in vivo Fishes:A Review

HAN Fei;ZHANG Man;ZHANG Zhou;WANG Jing-yu;Vocational and Technical College of Yangling;College of Veterinary Medicine,Northwest A&F University;  
Avermectin is a broad-spectrum antiparasitic agent.Due to its therapeutic effects,it has widely been used in aquaculture.It is not only used in livestock,but it has also been extensively used in fishery production.in parasitic nematodes and arthropods.However,if avermectin is improperly used in aquaculture,it results toxic effects in an aqueous environment and aquatic ecosystems.The present review focused on avermectin's action mechanism,drug toxicity and pharmacokinetics in aquatic animals.And this review also selectively analyzed the residue detection method and maximum residue limit in order to provide a reference to the research of assessing avermectin's toxicity and the control of avermectin's residue effects on aquatic organism.
【Fund】: 杨凌职业技术学院科学研究基金项目(A2012041)
【CateGory Index】: S948
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