Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Popular Science & Technology》 2014-12
Add to Favorite Get Latest Update

Advances in bone morphogenetic protein 2 in treatment of femoral head necrosis

With the development of tissue engineering, bone morphogenetic protein(bone morphogenetic protein, BMP) applications study is becoming more and more widely in the field of orthopedics,The therapeutic effect of bone morphogenetic protein-2(bone morphogenetic protein, BMP-2) including bone defects,nonunion and other aspects have been demonstrated on the basis of experimental and clinical practice[1-3],Its mechanism may be BMP-2 can induce differentiation of mesenchymal stem cells into cartilage direction,conduct through Smad pathway and MAPK pathway,and promote bone formation, tissue growth and damage repair[4]. Based on this mechanism of action, more and more scholars have putted study focuses on the field of femoral head necrosis treatment, this article makes a brief summary of the treatment of femoral head necrosis advances of BMP-2 in recent years.
【CateGory Index】: R681.8
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
Chinese Journal Full-text Database 10 Hits
1 CHEN Cong,KANG Quan,LUO Qing,DIE Xiao-hong,TIAN Wen Ministry of Education Key Laboratory of Child Development and Disorders,Key Laboratory of Pediatrics in Chongqing,Chongqing International Science and Technology Cooperation Center for Child Development and Disorders,Department of Hepatobiliary Surgery,Children's Hospital of Chongqing Medical University,Chongqing 400014,China;The effecf of bone morphogenetic proteins 2,7 in inducing murine embryonic stem cells into hepatic cells in vitro[J];Medical Journal of Chinese People's Liberation Army;2013-04
2 LV Yu-ming,CHENG Li-ming,PEI Guo-xian.Department of Orthopedics and Traumatology,Nanfang Hospital,Southern Medical University,Guangzhou 510515,China;Treatment of osteonecrosis of the femoral head with modified free vascularized fibular grafting and allogenic bone containing BMP[J];The Journal of Practical Medicine;2011-11
3 Cui Da-ping1,Zhao De-wei1,2 1Dalian University of Technology,Dalian 116023,Liaoning Province,China; 2Department of Orthopaedics,Zhongshan Hospital of Dalian University,Dalian 116001,Liaoning Province,China;Vascular endothelial cell growth factor combined with bone morphogenetic protein-2-modified bone marrow mesenchymal stem cells in repair of femoral head necrosis[J];Journal of Clinical Rehabilitative Tissue Engineering Research;2011-01
4 Zhong Sheng1,Liu Dan-ping1,Liu Su-wei2,Li Xiao-yu,Li Chen1,Li Yuan4 1Department of Bone and Joint Surgery,First Affiliated Hospital of Liaoning Medical University,Jinzhou 121000,Liaoning Province,China;2Department of Anatomy,Liaoning Medical University,Jinzhou 121000,Liaoning Province,China;3Second Department of Orthopaedics,West Hospital of Anshan City,Anshan 114012,Liaoning Province,China;4Third Department of Neurology,First Affiliated Hospital of Liaoning Medical University,Jinzhou 121000,Liaoning Provine,China;Construction and identification of vascular endothelial growth factor 121 and bone morphogenetic protein-2 genes co-expressing recombinant adenovirus vector[J];Journal of Clinical Rehabilitative Tissue Engineering Research;2011-20
5 Qi Xin-wen,Wang Zhao-jie,Chen Jun-ping,Zhao Jun-yan,An Rong-ze Department of Orthopedics,the Fifth Affiliated Hospital of Zunyi Medical College,Zhuhai 51900,Guangdong Province,China;Bone morphogenetic protein-2 combined with adipose derived stem cells for treatment of avascular necrosis of the femoral head in rabbits[J];Journal of Clinical Rehabilitative Tissue Engineering Research;2011-45
6 ZHOU Chuan-you,ZHU Ya-lin,HE Rui,HU Fei,WU Lü,SHANG Xi-fu.(The Secemd Department of Orthopaedics,Provincial Hospital Affilitated to Anhui Medical University,Hefei 230001,China);Experimental Study of BMSCs and rhBMP-2/rhVEGF on Early Steroid-induced Avascular Necrosis of Femoral Head in Rabbit[J];Medical Recapitulate;2011-12
7 Li Zirong, Sun Wei, Shi Zhencai, Wang Bailiang, Zhang Qidong, Guo Wanshou (Centre for Osteonecrosis and Joint-preserving & Reconstruction, China-Japan Friendship Hospital, Beijing 100029, China);Debridement and impacted bone graft mixed with and without bone morphogenetic protein for the treatment of osteonecrosis of the femoral head: a comparative study[J];Chinese Journal of Bone and Joint Surgery;2012-05
8 FEI Zhi-qiang,XIONG Jian-yi,LIU Zhi-yong,et al.Department of Orthopaedics,Shenzhen Second People's Hospital,National Key Clinical Specialist,Shenzhen Key Lab of Tissue Engineering Research Center,Shenzhen,Guangdong 518035,China;Enhancement of BMP binding peptide combined with recombinant human BMP-2 on the heal of a rodent segmental femoral defect[J];Orthopedic Journal of China;2013-12
9 CAO Xin1,CHEN Huijin2,CUI Zhengli1,JIN Gele2,YANG Yi1,WANG Yanan1,XIAO Wei1.1Orthopedic Center of Shengli Oilfield Central Hospital,Dongying Shandong,257000,P.R.China;2VIP Ward,Second Department of General Surgery,the First Affiliated Hospital of Xinjiang Medical University;CONCENTRATION-OR TIME-DEPENDENT MANNER OF RECOMBINANT BONE MORPHOGENETIC PROTEIN 2 IN REGULATING EXPRESSION OF VASCULAR ENDOTHELIAL GROWTH FACTOR[J];Chinese Journal of Reparative and Reconstructive Surgery;2013-08
10 ZHANG Yan-ru1,2,MA Hui3,ZHANG Hui4,WANG Yi-sheng1 1.Department of Orthopaedics,the First Affiliated Hospital of Zhengzhou University,Zhengzhou 450052,China;2.The International Education School of Zhengzhou University,Zhengzhou 450052,China;3.The Third People's Hospital of Luoyang City,Luoyang 471002,China;4.Clinical Medicine of Zhengzhou University,Zhengzhou 450052,China;The experimental study on the repair of ANFH in rabbit with the BMP-2 gene transfected autologons BMSCs[J];Chinese Journal of Clinical Anatomy;2013-04
Chinese Journal Full-text Database 10 Hits
1 DIE Xiaohong;LUO Qing;CHEN Cong;LUO Guangjin;KANG Quan;Ministry of Education Key Laboratory of Child Development and Disorders/Key Laboratory of Pediatrics in Chongqing/Chongqing International Science and Technology Cooperation Center for Child Development and Disorders,Children's Hospital,Chongqing Medical University;;Construction of a recombinant adenovirus co-expressing bone morphogenic proteins 9 and 6 and its effect on osteogenesis in C3H10 cells[J];Journal of Southern Medical University;2013-09
2 LI Lianbing;ZHANG Qiqing;HOU Zhiwei;ZHU Yijian;ZHANG Danyan;LV Jing;ZHAO Letian;YANG Zhixi;ZHU Minghua;MA Mingfu;Chongqing Population and Family Planning Institute of Science and Technology/Key Laboratory of Birth Defects and Reproductive Health of Birth Defects and Reproductive Health of National Health and Family Planning Commission;Institute of Biomedical Engineering,Chinese Academy of Medical Sciences;Sichuan Diseases Control and Prevention;;Experimental study on the effects of artificial bone composite materials on bone formation[J];Beijing Biomedical Engineering;2014-03
3 WANG Jian,HE Juan-wen,WANG Jin,HU Jin,LUO Jin-yong,ZENG Zhao-fang(Key Laboratory of Laboratory Medical Diagnostics designated by Chinese Ministry of Education,Faculty of Laboratory Medicine,Chongqing Medical University,Chongqing 400016,China);Inhibition of ERK1/2 kinase increases BMP9-induced osteogenic differentiation of C_3H10T1/2 mesenchymal stem cells[J];Laser Journal;2012-03
4 Marios G Lykissas;Alexander Aichmair;Department of Orthopaedic Surgery, Spine and Scoliosis Service, Hospital for Special Surgery, Weill Cornell Medical College, New York, NY 10021, United States;;Current concepts on spinal arthrodesis in degenerative disorders of the lumbar spine[J];世界临床病例报告杂志(英文版);2013-01
5 ZHANG Zheng,LI Chen,CHEN Jun-jiang,LIU Dan-ping(First Affiliated Hospital of Liaoning Medical University,Jinzhou 121001,P.R.China);Construction and identification of recombinant adenovirus shuttle plasimid expressing FLAG labeled BMP2 and traced by GFP[J];Shandong Medical Journal;2011-10
6 ZHAO Ying-Ze,ZHANG Yan,LUO Jin-Yong (Key Laboratory of Laboratory Medical Diagnostics,Ministry of Education,Chongqing Medical University,Chongqing 400016,China);Identification and Analysis of TypeⅡ TGFβ Receptors in BMP9 Induced Osteogenesis[J];Progress in Biochemistry and Biophysics;2010-10
7 YANG Chun-yu1,YANG Ming1,YANG Chun-li2,HE Mei1,QU-Min1,ZHANG Shuai1,XU Wei1,CHEN Feng-lian1,WANG Ping3 (1. College of Food Engineering,Harbin 150076,China; 2. College of Light Industry,Harbin University of Commerce,Harbin 150076,China; 3.Department of Food Science and Engineening,Forestry College,Northeast Forestry University,Harbin 150040,China);Research progress in separation and purification of bone morphogenetic protein-2[J];Science and Technology of Food Industry;2009-12
8 SONG Tao,HE Juan-Wen,WANG Jin,TANG Min,LUO Jin-Yong**(Key Laboratory of Laboratory Medical Diagnostics,Ministry of Education,Chongqing Medical University,Chongqing 400016,China);Inhibition of ERK1/2 Kinase Enhances BMP9-induced Osteogenic Differentiation of Mesenchymal Stem Cells[J];Progress in Biochemistry and Biophysics;2012-12
9 Gan Qiang Hu Zhenming Hao Jie Jiang Wei Shen Jieliang Wang Dawu Zhong Xiaoming Fang Ji(Department of Orthopaedics,the First Affliated Hospital,Chongqing University of Medical Sciences,Chongqing 40016,China);Purification and Biological Osteoinductive Activity Analysis of Recombinant Human Bone Morphogenetic Protein 9 by Eukaryotic Expression[J];Journal of Biomedical Engineering;2013-04
10 XU Jing;ZHAO Dan;WANG Jian;WANG Wen-Juan;LUO Jin-Yong;Key Laboratory of Laboratory Medical Diagnostics,Ministry of Education,Chongqing Medical University;Student Affair Office,Chongqing Medical University;;BMP9 Regulates Osteogenic Differentiation of Mesenchymal Stem Cells Through JNKs Kinase Pathway[J];Progress in Biochemistry and Biophysics;2013-12
【Secondary Citations】
Chinese Journal Full-text Database 10 Hits
1 Qiang Peng1, Ming Liu1, Shu-Min Song1, Xian-Hua Li2, Yi-Hua Du1, Yong Zhi1, Min-Yong Wang3 1 Department of Surgery, Affiliated Hospital of Luzhou Medical College, Luzhou, Sichuan 646000, P. R. China; 2 Physiology Laboratory, Luzhou Medical College, Luzhou, Sichuan 646000, P. R. China; 3 Central Laboratory, Luzhou Medical College, Luzhou, Sichuan 646000, P. R. China;The recruitment of exogenous endothelial progenitor cells in lung tumor model of nude mice[J];Chinese Journal of Cancer;2010-11
2 LuZifan,Liu Xinping,Chen Sumin,Chem NanchunDepartment of Biochemistry,Xi’ an 710033;C terminal peptide of hBMP2:high expression in E.coli and boneinductive activity[J];JOURNAL OF THE FOURTH MILITARY MEDICAL UNIVERSITY;1995-06
3 Zhao Dewei,Guo Zhe.Department of Orthopaedics,Dalian Railway Hospital,Dalian,116001.;The Operative Treatment of Ischemic Necrosis of Femoral Head under the Supervision of Arthroscope[J];The Journal of Bone and Joint Injury;2000-03
4 Wang Weiming,Zhao Dewei,Depatrment of Orthopaedics, 4 th Hospital,Dalian Medical University,Dalin,116001;An Experimental Research of Refrigeration with Liquid Nitrogen to ONFH[J];The Journal of Bone and Joint Injury;2001-06
5 Chen Bingpeng,Chang Fei,Wang Jincheng,et al.Department of Orthopedics,China-Japan Union Hospital of JiLin University, Changchun, 130033;Experimental Study of Core Decompression and Autografting Bone Marrow Derived Mesenchymal Stem Cell on Corticosteroid-Induced Femoral Head Osteonecrosis in Rabbits[J];Chinese Journal of Bone and Joint Injury;2010-01
6 He Zhongjie, Fang Chihua, Ma Junxun et al. Department of General Surgery, Zhujiang HospitaL, Nanfang Medical University, Guangzhou 510282, China;Rat mesenchymal stem cells differentiate into hepatocyte-like cells induced hepatocyte growth factor plus epidermal growth factor in vitro[J];Medical Journal of Chinese People's Liberation Army;2006-05
7 Zhou Gaosu, Zhang Zhenshu, Liu Side, et al. Department of Gastroenterology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China;Derivation, characterization and differentiation in vitro of hepatic oval cells of adult rats[J];Medical Journal of Chinese People's Liberation Army;2007-05
8 LI Dong-yan,YU Li,LI Fa-tao,LIU Hong,LUO Jing-zi(Department of Biochemistry,Medical College,Jinan University,Guangzhou 510632,China);The improvement of the extraction method for adipose tissue derived mesenchymal stem cells[J];Journal of Jinan University(Medicine Edition);2007-06
9 JIAO Qing-feng,SHANG Xi-fu;Study progress about the pathogenesis of steroid-induced osteonecrosis of the femoral head[J];Journal of Clinical Orthopaedics;2010-03
10 WANG Wei-jun, et al.(Ningxia Medical University, Yinchuan 750004, China);Primitive study on the expression of VEGF and BMP-2 of the local femoral head in steroid-ONFH[J];Ningxia Medical Journal;2009-02
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved