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《Clinical Medicine》 2006-10
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Relationship of albumin excretiontate and carotid intima-media thickness in newly diagnosed type 2 diabetic patients

LI Xiaoling,ZHU Lüyun.Department of Endocrinology,the Bethune International Peace Hospital,Shijiazhuang 050082,Hebei  
Objective To study the relationship of urinary albumin excretion rate(UAER) and carotid intima-media thickness(IMT) in newly diagnosed type 2 diabetic subjects.Methods Eighty-six newly diagnosed type 2 diabetic individuals were classified according to UAER into two groups in comparison with normal control subjects.And ultrasound measurement of the IMT of the common carotid artery was performed.Results The diabetic subjects,both men and women,displayed carotid intima-media thickness,which were significantly higher than normal controls.Among the coronary risk factors,IMT in the diabetic group was well correlated to albuminuria,HbAlc,C-peptide.Conclusion Newly diagnosed type 2 diabetic patients exhibit a higher degree of early atherosclerosis than normal controls and microalbuminuria appears to be a risk marker that cause IMT in the early phases of diabetes.
【CateGory Index】: R587.1;R543
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