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《Journal of Pediatric Pharmacy》 2004-02
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The observation of the damage of cardiomyocyte and the curative effect of high intravenous dose of vitamin C in infants with rotavirus diarrhoea .

Feng Mei (The Frist Peopls's Hospital Hangzhou, Zhejiang Hangzhou 310006, China)  
Objective: To evaluate the damage of cardiomyocyte that might be involved in infants with rotavirus (RV) diarrhoea and the curative effect of high dose of vitamin C. Methods: We determined AST and CK-MB in 76 infants with RV diarrhoea, and treated 39 of those infants, who showed abnormal myocardial with high dose of vitamin C. Results: AST and CK-MB were increased in infants with RV diarrhoea, whatever lossing fluid and salts in the faeces, and were decreased after being treated with high dose of vitamin C 4~6 days later. Conclusion: We should pay medical attention to myocardial function of infants with RV diarrhea, and high dose of vitamin C can protect cardiomyocytes from damage.
【CateGory Index】: R725.1
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【Co-citations】
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