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《Journal of Pediatric Pharmacy》 2005-03
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The curative effect of Curosurf in prevention hyaline membrane disease of prematures

LIU Qi-ming,CAO Nan-hua,HU Chun-fang,et al(Women and Child Health Hospotil of Jingdezhen,Jiangxi Province,Jiangxi Jingdezhen 333000,China)  
Objective: This prospective study was designed aiming at determining of the effect of Curosurf in prevention of hyaline membrane disease of prematures. Methods: Thirty-six preterm infants with gestational age of 27~32 weeks and birth weight of 950~1200g were assigned to be prevented from respiratory disease syndrome (NRDS). Among them, 17 neonates of treated group were dripped in with Curosurf through trachea within 6h of life and 19 neonates of control group without. Results: The incidences of NRDS, mortality and mechanical ventilation dependence in treated group were obviously less than control group(P 0.05). Conclusion: The preventive administration of Curosurf for prematures can reduce the rate of RDS and mechanical ventilation dependence, decrease mortality and complication, and improve the prognosis.
【CateGory Index】: R722.6
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