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《Journal of Pediatric Pharmacy》 2007-03
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A clinical observation on efficacy of ribavirin spray on herpangina

HE Shuang-wen (The people's Hospital of Gongyi City,Henan Gongyi 451200,China)  
Objective:To observe the clinical efficacy of ribavirin spray in treating herpangina.Methods:76 cases with herpangina were randomly divided into the control group of 36 cases and the treatment group of 40 cases.Two groups were given regular treatment,with the treatment group given ribavirin spray in addition,once every 2 hours,total 8 times on first day and every 4 hours,4 times a day,2~3 sprays for each time on the following 5 to 7 days.Results:The total effective rate and the rate of excollent effect in treatment group were 92.5% and 70.0% respectively, and 72.2% and 38.9% in control group and the physical signs such as body temperature,oral ulcer got better in a shorter time in the treatment group than in the control group,so there was a significant difference between the two groups.Conclusions:Ribavirin spray could be effectively and safely used in treating herpangina with little side effects.It can he used as a first choice for herpangina.
【CateGory Index】: R766
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