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《Journal of Pediatric Pharmacy》 2007-05
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Study of tachypleus amebocyte lysate test for bacterial endotoxins in Glycyl-Glutamine

LIU Hua~(1,2) HUANG Ming~2 ZHOU Li~2 (1.China Pharmaceutical University,Jiangsu Nanjing 210000,China;2.Sichuan Provincial Institute of Food and Drug Control,Sichuan Chengdu 610036,China)  
Objective:To confirm the feasibility of bacterial edotoxins test for Clycyl-Glutamine.Methods:After interfering test,tachypleus amebocyte lysate (TAL) test was adopted to detect bacterial endotoxins in Glycyl-Glutamine.Results:Three batches of Glyeyl-Glutamine showed no vir-repression with the test,after the samples were diluted to 20 mg/mL,10 mg/mL and the contents of bacterial endotoxirm in all samples were not more than 0.025 EU/mg.Conclusions:TAL test provides a new way to detect bacterial endotoxins in Glyeyl-Glutamine.
【CateGory Index】: R927
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【Citations】
Chinese Journal Full-text Database 1 Hits
1 XIAO Gui-nan,LI Jin-fei,WU Zhao-di(Guangdong Institute for Drug Control,Guangzhou 510180,China);Tachypleus amebocyte lysate test for bacterial endotoxins in Aceglutamide and sodium chloride injection[J];West China Journal of Pharmaceutical Sciences;2006-04
【Co-citations】
Chinese Journal Full-text Database 2 Hits
1 YAN Qing-ying,CHENG Yu-lei,CAI Zhi-bo(The Children’s Hospital affiliated to Zhejiang University Medical College,Zhejiang Hangzhou 310003,China);The bacteria endotoxin test for monitoring pyrogen in netilmicin sulfate of glucose and sodium chloride injection[J];Journal of Pediatric Pharmacy;2005-03
2 XIAO Gui-nan,LI Jin-fei,WU Zhao-di(Guangdong Institute for Drug Control,Guangzhou 510180,China);Tachypleus amebocyte lysate test for bacterial endotoxins in Aceglutamide and sodium chloride injection[J];West China Journal of Pharmaceutical Sciences;2006-04
【Secondary Citations】
Chinese Journal Full-text Database 1 Hits
1 TONG Hui-zhen,WU Zhao-di,XIAO Gui-nan (Guangdong Institute for Drug Control, Guangzhou 510180, China);Tachypleus amebocyte lysate test for bacterial endotoxins in raltitrexed for injection[J];West China Journal of Pharmaceutical Sciences;2004-05
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