The curative effect of high intravenous immunoglobuin in treatment of Staphylococcal Scalded Skin Syndrome
ZHANG Wen-yong 1,WANG Xiao-gang2,TANG Xue-mei 2(1. Xuanhan Women and Chidren Healthy Hospital of Sichuan Province,Sichuan Xuanhan 636150,China;2. The Children’s Hospital of Chongqing Medical University,Chongqing 400014,China)
Objective:To study the effect of intravenous immunoglobulin (IVIG) in the treatment of staphylococcal scalded skin syndrome (SSSS).Methods:From March 2003 to May 2007, 75 patients with SSSS were hospitalized in the children’s hospital of Chongqing medical university. As the control group, 35 cases had used antibiotic, and other 40 cases were treated with antibiotic and IVIG as treatment group,with IVIG 1 g/(kg·d) for 1~2 days. Then the time of normal body temperature, of the skin erythema and herpes stopping growing and to dry, and their duration in hospital were comparied.Results:The time of normal body temperature, of the skin erythema and herpes stopping growing and to dry, and their duration in hospital were (2.9±1.46) days,(6.03±1.44) days, (3.87±1.37) days,(3.08±1.14) days in the treatment group, while (4.86±2.67) days,(8.43±2.92) days,(6.09±2.33) days,(4.51±1.9) days in the control group.The total effective rate and the rate of excellent results in the treatment group were 100% and 80.0%, but 71.4% and 37.1% in the control group.There was a significant difference between the two groups (P0.01).Conclusions:High IVIG is effective in the treatment of SSSS,which can rapidly improve the chief symptoms and promote the curaitive rate.
【CateGory Index】： R753