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《Journal of Pediatric Pharmacy》 2008-06
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Effect of inhaled budesonide with nebulizer for children with acute laryngitis

LIU Wei,CHEN Ren-jie(The Second Affiliated Hospital of Nanjing Medical University,Jiangsu Nanjing 210011,China)  
Objective:To observe the therapeutic effect of inhaled budesonide aerosol and application of systemic glucocorticoid on acute laryngitis of children.Methods:61 children with acute laryngitis in clinic and wards of this hospital from September 2006 to September 2007 were divided into the treatment group with inhaled budesonide aerosol(35 cases) and the control group with prednisolone or dexamethasone(26 cases).Results:The symptom-free time of inspired laryngeal stridor,dog bark-like cough and hoarseness is respectively(1.81±0.23)d,(2.31±1.15)d,(3.23±0.54)d in the treatment group(35 cases),however that of the control group is respectively(2.86±1.74)d,(3.62±2.37)d,(5.09±2.85)d.The difference of the symptom-free time between the treatment group and the control group was significant(P0.01).Conclusions:Budesonide aerosol inhalation has an instant effect quicker than methylprednisolone and dexamethsone injection.This method,easy to use,can shorten treatment time and can be applied widely in clinic instead of systemic glucocorticoid.
【CateGory Index】: R767
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【References】
Chinese Journal Full-text Database 1 Hits
1 LI Wen-ying,FU Wan-hai,HE Yi-qi,ZHANG Xiao;Curative Effects of Budesonide Suspension Combined with Ribavirin on Acute Laryngitis in Children[J];Journal of Applied Clinical Pediatrics;2009-16
【Citations】
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【Co-citations】
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1 LIAO Xian-hua, XU Yu-xia, GU Zhi-yong;The Observation of Cli mical Effect fromInhaling Pul micort Respuls for Chidren With Acute Infectious Laryngitis[J];West China Medical Journal;2007-02
2 WU Bin,LIN Bin-rong,LIN Xi,LIU Jian,TANG Qiu-yu(Department of Pediatrics,The First Affiliated Hospital of Fujian Medical University,Fuzhou 350005,Fujian,China);Effect of inhaled budesonide with nabulizer for children with acute laryngitis[J];Journal of Clinical Pediatrics;2008-03
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【Co-references】
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1 WU Bin,LIN Bin-rong,LIN Xi,LIU Jian,TANG Qiu-yu(Department of Pediatrics,The First Affiliated Hospital of Fujian Medical University,Fuzhou 350005,Fujian,China);Effect of inhaled budesonide with nabulizer for children with acute laryngitis[J];Journal of Clinical Pediatrics;2008-03
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【Secondary Citations】
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1 HAN Wei,ZHOU Xin(Department of Respiration,First People′s Hospital of Shanghai Jiaotong University,Shanghai 200080);NEBULIZED BUDESONIDE IN THE TREATMENT OF ACUTE EXACERBATIONS OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE[J];Journal of Jiangsu Clinical Medicine;2004-02
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