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《Chinese Journal of Child Health Care》 1998-02
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Investigation of Cellular Immune Status and Effect of Lentinan on the Patients with Recurrent Respiratory Tract Infection in Children

Liu Shixin , Li Nanxing, Fei Hongbao. Shenzhen Hospital for Women and Children , Shenzhen 518028  
ve To investigate the cellular immune status of child patients with recurrentrespiratory tract infection(RRTI) . Methods 105 cases were detected T-subgroup, IL-2 receptor, IL-2 activity , red blood cell C3b receptor rosette (RBCC3bRR) and immune complex rosette(RBCI-cR). The patients were randomly divided into two groups: 1)60 cases were treated by dry syrups of lentinan; 3)45 cases by levomizole for three months. Both were followed up for six months. Results CD3+ , CD4+ , CD8+ lymphocyte, CD4+ /CD8+ , IL-2 and RBCC3bRR decreased significantly in patients with RRTI while RBCIcR increased. After treatment of lentinan, their cellular immunity improced dramatically. Clinic efficacy of lentinan reached 96.6 % , much higher than that of levomizole(77.6% , P 0. 01). Conclusion RRTI children had cellular immune deficiency, and admministration of lentinan can enhance their cellular immunity and reduce considerably the incidence.
【CateGory Index】: R725.6
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