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《Chinese Journal of Child Health Care》 2007-05
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Preventable effects of the lonicera extract from water solution on intestinal microflora of the ovalbumin-induced BALB/c Mice

RAN Yu-chen,LI Hai-qi.(Department of Children Hedlth Care, Children Hospital of Chongqing Medicd University,Chongqing,400014,China)  
[Objective] To investigate the preventable effects of the Lonicera ext on intestinal microflora of the ovalbulmin-induced BALB/c mice. [Methods] Female BALB/c sensitized mice were randomly divided into preventive group (group Y ) , therapeutic group(group T) or the positive control group(group Ch) . The normal mice were set as the negative control (group NS). Group Y and group T were fed with 100% of the Lonicera ext as group YH and TH , given 50% the Lonicera ext as group YM and TM , and fed with 25% the Lonicera ext as YL and TL .The levels of the OVA-specific IgE in serum of the mice were measured , and the tissues of small intestine were histologically examined by either HE and toludine blue stain. [Results] ①The levels of OVA-specific IgE in serum in group Y and T were reduced after being treated by gavage with 100% or 50% of the Lonciera extract,the significant inflammatory reactions were inhibited in the mice of group YH , YM ,TH and TM .②The accumulated and degranulated mast cells in lamina propria were statistically reduced in the mice of group YH , YM ,TH and TM by gavage with 100% or 50% of the Loncera ext. [Conclusion] The Lonicera ext OVA-induced allergic response in mice could not be prevented by the Lonicera ext.
【CateGory Index】: R285.5
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