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《Chinese Journal of Lung Cancer》 2001-05
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The general measurement of genetic factors on lung cancer in Xuanwei, China

JIN Yongtang , ZHOU Xiaotie, HE Xingzhou. Department of Environmental Health, Anhui Medical University, Hefei, Anhui 230032, P.R.China  
Objective To investigate the hereditary model of lung cancer and to determine measurement of genetic factors on lung cancer. Methods With methods of genetic epidemiology, 370 probands of lung cancer and 370 spouses of the probands (control) were studied. Results The segregation ratio of lung cancer was 0.15 and the genetic model of lung cancer belonged to polygenetics.The heritability of lung cancer was 24.6%, 14.6% for male and 37.8% for female. Conclusion The genetic model of lung cancer is polygenetics.The genetic susceptibility of female with lung cancer is higher than that of male. The genetic factor is one of the risk factors on lung cancer but the environmental factors are still the most important risk factors.
【CateGory Index】: R734.2
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1 YANG Hong-sheng, DENG Yong-jun, LI Ji-mei, CHAO Hu, SHI Yun-fei (Dept. of Thoracicsurgery, The 1st Affiliated Hospital of Kunming Medical College, Kunming 650032,China);Comparative Study of Expression and Mutations of Ras Gene in Patients with Non-small-cell Lung Cancer of Xuanwei and Kunming[J];Academic Journal of Kunming Medical College;2004-01
【Co-citations】
Chinese Journal Full-text Database 1 Hits
1 Zhang HongshengShandong provincial Environmental Health Monitoring Station;Study on Hereditary Epidemiology of Water Pollution in Mata Lake District[J];Journal of Environment and Health;1989-03
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1 MENG Zi qiang\+1, ZHANG Lian zhen\+2 (1. Institute of Environmental Medicine and Toxicology, Shanxi University, Taiyuan 030006,China; 2. China Institute for Radiation Protection, Taiyuan 030006, China);DNA OXIDANT DAMAGE INDUCED BY TOBACCO SMOKE IN HUMAN BLOOD LYMPHOCYTES[J];Carcinogenesis,Teratogenesis and Mutagenesis;2001-03
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