Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Chinese Journal of Lung Cancer》 2004-04
Add to Favorite Get Latest Update

Gefitinib molecular target therapy for Chinese patients with non-small cell lung cancer

WU Yilong, YANG Xuening, YANG Jinji, HUANG Yujuan. The Lung Cancer Research Institute and Cancer Center, Guangdong Provincial People’s Hospital, Guangzhou, Guangdong 510080, P.R.China  
Objective To explore the experience of gefitinib molecular target therapy for Chinese patients with non small cell lung cancer (NSCLC). Methods The unpublished data of gefitinib for advanced NSCLC in 7 hospitals were collected. The detailed data from Guangdong Provincial People’s Hospital were analyzed. Results A total of 282 patients with advanced NSCLC was treated with gefitinib from July 2001 to December 2003. Response rate was 22.2% 47.7%, disease control rate 62.6% 81.8%. No severe side effects were surveyed. Conclusion Gefitinib can be used safely and effectively in Chinese patients with advanced NSCLC.
【CateGory Index】: R734.2
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
【References】
Chinese Journal Full-text Database 7 Hits
1 ZHANG Yang1,2, ZHANG Li1,2, XU Fei1,2, WANG Zhi-Qiang1,2, ZHAO Hong-Yun1,2, GUAN Zhong-Zhen1,2, XU Guang-Chuan1,2, PAN Zhen-Kui1,2 1. State Key Laboratory of Oncology in South China, Guangzhou, Guangdong, 510060, P. R. China 2. Department of Medical Oncology, Cancer Center, Sun Yat-sun University, Guangzhou, Guangdong, 510060, P. R. China;Efficacy of Gefitinib on Advanced Non-small Cell Lung Cancer in Expanded Access Program (EAP)[J];Chinese Journal of Cancer;2006-12
2 LIU Xiao-Qing~(*),TANG Chuan-Hao,GAO Hong-Jun,Li Jian-Jie,WANG Wei-Wei (Department of Lung Cancer,Affiliated Hospital,Academy of Military Medical Sciences,Beijing 100071,China);Gefitinib monotherapy for patients with advanced non-small cell lung cancer[J];Bulletin of the Academy of Military Medical Sciences;2006-05
3 ;分子靶向药物吉非替尼治疗非小细胞肺癌研究进展[J];;2008-02
4 AN She-juan,CHEN Zhi-hong,WANG Zhen,ZHU Jian-quan,XIE Zhi,CHEN Shi-liang,LIN Jia-ying,GUO Ai-lin,WU Yi-long (Research Center of Medical Sciences,Guangdong Provincial People's Hospital,Guangdong Provincial Lung Cancer Research Institute,Guangzhou 510080,China);Correlations between the Expression Levels of Laminin 5 and Epidermal Growth Factor Receptor in Tumor Tissues of Patients with Lung Cancer[J];The Journal of Evidence-Based Medicine;2007-02
5 LI Zi-ming,LIAO Mei-lin(Shanghai Chest Hospital,Shanghai Clinical Lung Tumor Medical Center,Shanghai 200030,China);New developments in advanced non-small cell lung cancer[J];China Oncology;2007-11
6 LAI Ren- sheng , XIE Ling, SHEN Long-shu, ZHU Chang-le, QIAN Jun. Department of pathology, Affiliated Hospital of Nanjing TCM University, Nanjing 210029, China; Department of Oncology, PLA Canceer Center in Nanjing;Epithelial growth factor receptor (EGFR) exon double-sequencing analysis in NSCLC[J];Chinese Journal of Oncology;2006-08
7 ZHANG Zi-jin~(1,2),CHENG Gang~2(1 Graduate School of Peking Union Medical College,Beijing 100730,China;2 Department of Medical Oncology,Beijing Hospital,Beijing 100730,China);Advances of molecular targeted therapy for non-small cell lung cancer[J];Chinese New Drugs Journal;2005-10
【Citations】
Chinese Journal Full-text Database 2 Hits
1 Wu Yilong Lung Cancer Research Center, The Third Affiliated Hospital, Sun Yat-sen University, Guangdong Scientific Research Center of Evidence-Based Medicine, Guangzhou 510630, P.R.China;Targeted therapy of ZD1839 for lung cancer[J];The Journal of Evidence-based Medicine;2002-04
2 WU Yi long,LIN Jia ying,YANG Xue ning,et al Lung Cancer Research Institute & Cancer Center,Guangdong Provincial People's Hospital,Guangzhou 510080,China;The Complexity of the Abnormal Tyrosine Kinase Signaling Pathway in Lung Adenocarcinoma[J];Cancer Research On Prevention and Treatment;2004-02
【Co-citations】
Chinese Journal Full-text Database 5 Hits
1 JU Wen-dong, SHI Wei-jian, ZHOU Qiao-yun, WU Jian-hui Boai Hospital of Zhongshan City, Zhongshan 528403, P.R.China;One case report of polycythemia vera companied with lung cancer widespread transfer and literature review[J];Journal of Qilu Oncology;2005-19
2 Wu Yi- long Author's address Cancer Center, Guangdong Provincial People's Hospital, Guangdong Provincial Lung Cancer Research Institute, Guangdong Scientific Research Center of Evidence-Based Medicine, Guangzhou 510080, P.R.China;Lung cancer research influencing clinical practice[J];The Journal of Evidence-based Medicine;2003-04
3 Wu Yilong Author's address Guangdong Provincial Lung Cancer Research Institute,Cancer Center,Guangdong Provincial People's Hospital,Guangdong Scientific Research Center of Evidence-Based Medicine,Guangzhou 510080,P.R.China;Individualized molecular targeted therapy for lung cancer[J];The Journal of Evidence-based Medicine;2004-02
4 CHENG Chao 1, WU Yi long 2,GU Li jia 1, WENG Yi min 1 ,FENG Wei neng 1,ZHONG Wen zhao 1,HUANG Shao hong 1 1.Department of Thoracic Surgery, The Third Affiliated Hospital SUN Yat sen University,Guangzhou 510630,China;2. Cancer Center of Guangdong Province Hospital;The Exploration of The Recurrence free and Prognostic Factors in Right Resected PN2 Non small Cell Lung Cancer[J];Cancer Research On Prevention and Treatment;2004-11
5 LIN Jia-ying 1, WU Yi-long 2* ,YANG Xue-ning 3, CHEN Gang 3 1.Guangdong Provincial Research Institute of Lung Cancer, Research Center of Medical Sciences,Guangzhou 510080,China;2.Department of Lung cancer;3.Department of Thoracic Surgery;Preliminary Analysis of Tyrosine Kinase Signaling Pathway in Different Prognosis Patients with Lung Adenocarcinoma[J];Cancer Research On Prevention and Treatment;2005-06
China Proceedings of conference Full-text Database 1 Hits
1 ;不同预后的肺腺癌患者酪氨酸激酶信号传导通路异常的初步探讨[A];[C];2004
【Co-references】
Chinese Journal Full-text Database 10 Hits
1 PAN Zhen-Kui, ZHANG Li, ZHANG Xing, WANG Xin, LI Ning, XU Fei, CHANG Jian-Hua, GUAN Zhong-Zhen Skate Key Laboratory of Oncology in Southern China, Cancer Center, Sun Yat-sen University, Guangzhou, Guangdong, 510060, P. R. China;Epidermal Growth Factor Receptor Mutation in Chinese Patients with Non-small Cell Lung Cancer[J];Chinese Journal of Cancer;2005-08
2 GUAN Zhong-Zhen1, ZHANG Li1, LI Long-Yun2, JIANG Guo-Liang3, LIU Xu-Yi4, CHU Da-Tong5, ZHAO Hong-Yun1, LI Wei6 1. Skate Key Laboratory of Oncology in Southern China, Cancer Center, Sun Yat-sen University, Guangzhou, Guangdong, 510060, P. R. China 2. Department of Respiratory Disease, Union Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, 100730, P. R. China 3. Department of Radiology, Cancer Hospital, Fudan University, Shanghai, 200032, P. R. China 4. Department of Medical Oncology, Beijing Cancer Hospital, Beijing, 100036, P. R. China 5. Department of Medical Oncology, Cancer Hospital, Chinese Academy of Medical S cience and Peking Union Medical College, Beijing, 100021, P. R. China 6. AstraZeneca Pharmaceutical Co Ltd R&D, Shanghai, 200041, P. R. China;Efficacy of Gefitinib on Chinese Patients with Locally Advanced or Metastatic Non-small Cell Lung Cancer: a Clinical Trial[J];Chinese Journal of Cancer;2005-08
3 ZHANG Yang1,2, ZHANG Li1,2, XU Fei1,2, WANG Zhi-Qiang1,2, ZHAO Hong-Yun1,2, GUAN Zhong-Zhen1,2, XU Guang-Chuan1,2, PAN Zhen-Kui1,2 1. State Key Laboratory of Oncology in South China, Guangzhou, Guangdong, 510060, P. R. China 2. Department of Medical Oncology, Cancer Center, Sun Yat-sun University, Guangzhou, Guangdong, 510060, P. R. China;Efficacy of Gefitinib on Advanced Non-small Cell Lung Cancer in Expanded Access Program (EAP)[J];Chinese Journal of Cancer;2006-12
4 CAO Kajia,MAO Zhida, CUI Nianji, et al Department of Radiotherapy, Cancer Center, Sun Yatsen University of Medical Sciences, Guangzhoun 510060, China;Influence of radiotherapy on the effectiveness of chemotherapy in patients with limited and extensive stages of small cell lung cancer (SCLC)[J];CHINESE JOURNAL OF CANCER;1999-03
5 Yan Shilin Li Weihong Gao Feng Lin Chenqing (The University of Tradional Chinese Medicine of Chengdu, Chengdu 610075, China);The research of cold and heat syndrome about advanced primary branchogenic carcinoma[J];Oncology Progress;2004-02
6 Li Jinhan Dept.of Oncology,Nanfang Hospital,Southern Medical University,Guangzhou 510515,China;The treatment of non-small cell lung cancer with integrated traditional Chinese medicine and Western medicine:Improving survival[J];Oncology Progress;2006-06
7 HUANG Zhu-hua,PU Chun-hua,ZHOU Zheng-guang,XIE Guang-long,LIU Xin-qun,YE Hong,LIN Nan (Department of Medical Oncology,Affiliated Hospital of Bengbu Medical College,Bengbu 233004,China);Ultra sound-guided aspiration biopsy in diagnosis of peripheral lung cancer[J];Journal of Bengbu Medical College;2006-04
8 Pan minqiu et al.(Affiliated Clinical Institute of Hunan Academy of TCM, Hunan);80 Cases of Primary Bronchial Pulmonary Squamous Cell Carcinoma Treated with Chinese Herbs and Chemotherapy[J];;1990-03
9 ;Development of surgical treatment of lung cancer[J];Acta Academiae Medicinae Militaris Tertiae;2005-20
10 ZHOU Qinghua , YAN Xi, REN Li, LI Lu, QIU Meng, YANG Yuqiong, LUO Deyun, HUANG Wenxia, LIU Luming, CHEN Zhen, MENG Zhiqiang, WANG Yajie, FU Qiang, XU Yang, YANG Linjun, LI Mingzhong, LI Enxiao, LI Yi, YAO Yu, ZHANG Xiangfu, LIU Xing, LU Huishan, ZHANG Maohong, WANG Xiuwen, YU Xuejun, QIN Fengzhan, ZHENG Rongsheng, CHEN Yuqing, BI Minghong. Cancer Center, West China Hopital, Sichuan University, Chengdu, Sichuan 610041, P.R.China;A multicenter randomized phase Ⅲ trial of domestic product of rmhTNF in the treatment of non-small cell lung cancer[J];Chinese Journal of Lung Cancer;2003-04
【Secondary References】
Chinese Journal Full-text Database 10 Hits
1 Yuan-Yuan Zhao,1,2 Yang Zhang,1,2 Hong-Yun Zhao,1,2 Jing-Xun Wu,1,2 Wei Jiang,1,2 Cong Xue1,2 and Li Zhang1,21.State Key Laboratory of Oncology in South China,Guangzhou,Guangdong,510060,P.R.China 2.Department of Medical Oncology,Sun Yat-sen University Cancer Center,Guangzhou,Guangdong,510060,P.R.China;Predictive factors for response and survival of gefitinib-treated locally advanced or metastatic non-small cell lung cancer patients:a retrospective analysis of two phase II clinical trials[J];Chinese Journal of Cancer;2009-06
2 Wanfeng GUO, Hongjun GAO, Xiaoqing LIU Department of Lung Cancer, Affiliated Hospital, Academy of Military Medical Sciences, Beijing 100071, China;A Case Report of Patient with Advanced Non-small Cell Lung Cancer by Five Times EGFR-TKIs Therapy[J];Chinese Journal of Lung Cancer;2013-06
3 HU Shou-you,FANG Liang-hua,XIE Ling,TANG Xiang,LAI Ren-sheng.Department of Oncology,Traditional Chinese Medical Hospital of Jiangsu Province,Nanjing 210009,China;Gene detection of turmor cells in fluid sample[J];Chinese Clinical Oncology;2009-12
4 Zhang Ningling(Department of Oncology,Affiliated Hospital of North Sichuan Medical College,Nanchong City,Sichuan,637000);Analysis on Molecular Targeted Therapy for Lung Cancer[J];Anti-tumor Pharmacy;2012-02
5 LIU Xiao-juan, ZHANG Miao-yan, LI Yu-ju, ZHAO Ai-jun, ZHENG Mao-gen. Depatment of Respiratory Medicine, Kailuan Majiagou Hospital, Tangshan 063021, Hebei, CHINA;Efficacy of gefitinib and the effect of gefitinib on the expression of EGFR by in the treatment of non-small cell lung cancer[J];Hainan Medical Journal;2013-04
6 YAO Han-qing;WANG Zheng-dong;JIANG Zheng-hua;ZHU Xiang-ping;HUANG Qian;Department of Respiratory Medicine,Clinical Medical College of Yangzhou University,Subei People's Hospital;;Effect of iressa on advanced non-small cell lung cancer[J];Practical Pharmacy and Clinical Remedies;2013-09
7 WANG Peng,LIU Chang-ting,SUN Bao-jun,QIAN Xiao-shun,LIU Qing-hui Department of Respiratory Medicine,South Building,General Hospital of PLA,Beijing 100853,P.R.China;Clinical analysis of gefitinib in treatment of elderly patients with non-small cell lung cancer[J];Chinese Journal of Cancer Prevention and Treatment;2010-15
8 WANG Jian-rong,ZHANG Shu-peng,LAI Ren-sheng Affiliated Hospital of Nanjing University of TCM,The Third Grade Laboratory of Molecular Biology of State Administration of TCM,Nanjing 210029,China;Intron 1 (CA)n dinucleotide repeat polymorphism and mutations of epidermal growth factor receptor and responsiveness of molecular targeted therapy in lung cancer[J];Journal of Modern Oncology;2009-11
9 LIU Fu-yin,WANG Jun,FAN Wei-fei,YANG Min,MENG Li-juan.Department of Oncology,Jiangsu Province Geriatics Hospital,Nanjing 210024,China;Study of gefitinib in the treatment of the elderly patients with advanced non-small cell lung cancer[J];Practical Geriatrics;2009-05
10 XIE Xiao-dong,ZHENG Zhen-dong,QU Shu-xian,et al.Oncology Department,General Hospital of Shenyang Military Region,Shenyang 110016,China;Clinical effect of Gefitinib(Iressa)in 51 cases of none-small cell lung cancer(NSCLC)[J];Chinese Journal of Practical Internal Medicine;2007-16
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved