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《Journal of Hubei Institute for Nationalities(Medical Edition)》 2006-01
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An Experimental Research on Bacteria-inhibiting and Anti-Inflammation Effects of Ethanolic Extract from Euonymus Alatus

GU Shu-zhen(Medical college of Hubei Institute for Nationalities,Enshi 445000,China)  
Objective To study the effects of ethanolic extract from euonymus alatus in bacteria-inhibiting and anti-inflammation.Methods The antibiotic activities of the active componet of Staphylococcus aureus,Escherichiu coli and Pseudomonas aeruginosa were preliminarily tested by Neo-Sensitab disk-diffusion method.In mouse of DTH models upon challenge with PC,obserseved he effects of EAL on the early and late phases by administration after antigen challenge.Results It was shown that EAL exerted bacteriostatic action on Staphylococcus aureus and Escherichiu coli.Moreover,its effects on the later were superable to the former.While it had no effects on Pseudomonas aeruginosa.The anti-inflammation effect of EAL is that it can restrain DTH,and the effects were stronger on the late phase than early.Conclusion EAL have certain effects on bacteria-inhibiting and anti-inflammation.Its flavanid is the active component to restrain DTH.
【Fund】: 湖北省教育厅重点资助课题(2004D004)
【CateGory Index】: R285.5
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