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《Journal of Hubei Institute for Nationalities(Medical Edition)》 2006-02
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The Effects of the Chief Components Isolated from Euonymus Alatus on Scavenging Oxygen Free Radical

HUANG De-bing,YU Zhao-fen(Department of Pharmacology,Hubei Institute for Nationalities,Enshi 445000,China)  
Objective To observe the effect of the chief components isolated from Euonymus Alatus on scavenging oxygen free radical.Methods Total Flavonolds of Euonymus Alatus(TFEA)、total Steroids of Euonymus Alatus(TSEA) and total Polysaccharide of Euonymus Alatus(TPEA) were isolated from Euonymus Alatus,the effect of which on scavenging oxygen free radical were studied using Luminal chemiluminescence(CL) emitted by Xanthine/Xanthine oxidase(Xan/XO) and Phorbol-12-myristate-13-acetate(PMA) stimulated Polymorphonuclear leaukocytes(PMN) and lipid-peroxidation of rat liver homogenate induced by H_2O_2-Fe~(2+).Results It showed that both TFEA and TSEA possessed the ability for scavenging oxygen free radical.The effect of TFEA was stronger than that of TSEA.Conclusion: Euonymus Alatus possessed the ability for scavenging oxygen free radical,its the chief components are TFEA,TSEA and TPEA.
【Fund】: 湖北省自然科学基金项目[2005]28-2005ABA197
【CateGory Index】: R285.5
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