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《Journal of Public Health and Preventive Medicine》 2011-06
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Study on embryo toxicity of Bensulfuron-methyl in zebrafish

HU Chuan-lu,YU Xiao-wei,ZHAO Zhan-ke,YUAN Jun-lin,YANG Xu Laboratory of Environmental Science,College of Life Science, Central China Normal University,Wuhan 430079,China  
Objective To determine the developmental toxicity of Bensulfuron-methyl on zebrafish embryo.Methods The fertilized eggs of zebrafish were exposed to seven different concentrations of Bensulfuron-methyl(0,20,40,60,80,100 and 120 mg·L-1).Embryo development,cumulative mortality rate,hatching ratio of zebrafish were observed under inverted microscope.Results The results indicated that spinal flectional abnormalities,pericardial edema and conjunction of larvae bodies were found in exposing to the concentration at 100mg·L-1 and 120 mg·L-1 respectively.The exposure concentrations of Bensulfuron-methyl that had significant negative effect of death and hatching on zebrafish embryo were 80mg·L-1 and 60 mg·L-1 respectively.After being exposed to Bensulfuron-methyl for 108 hours,the content of MDA detected in larvae appeared as dose-dependent manner.Conclusions Bensulfuron-methyl has certain inhibitory effect on the embryonic development of zebrafish.
【Fund】: 国家自然科学基金面上项目(编号:51076079)
【CateGory Index】: R114
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