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《JOURNAL OF FUDAN UNIVERSITY》 1999-05
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Cytotoxicity of Autonomous Parvoviral Non structural Protein NS1 to Transformed Cells and the Mechanism in Its Regulation of DNA Replication and Transcription

LUO Zu yu,SHI Zhi yi,LIN Wan min (Department of Physiology and Biophysics)  
Autonomous parvovirus has transformed cell specific toxicity. Its non structural protein NS1 plays an important role in the process of cytotoxic action. In parvoviral life cycle NS1 regulates DNA replication and transcription. The possible molecular mechanisms include trans inhibition of DNA replication,trans inhibition of gene expression and trans activation of transcription.
【Fund】: 国家自然科学基金
【CateGory Index】: Q939.4
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【Citations】
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【Co-citations】
Chinese Journal Full-text Database 7 Hits
1 YAN Wen-qing,WU De-feng,DAI Ya-dong,LIN Yong-li(College of Animal Science,Fujian Agricultural and Forestry University,Fuzhou,Fujian,350001,China);Study on the Pathogeny of Canine parvovirus[J];Progress in Veterinary Medicine;2006-01
2 WANG Jian-ke,CHENG Shi-peng,YAN Xi-jun,WU Wei(Institute of Special Wild Economic Animal and Plant Science,CAAS,Jilin,Jilin,132109,China);Progresses on Molecular Diagnostic Techniques and Genetically Engineering Vaccine of Mink enteritis virus[J];Progress in Veterinary Medicine;2008-10
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4 ZHAO Liang HU Jian-min YANG Jian-cheng XU Xing-li WU GAO-feng JIAO Yang (Department of Animal Science and Veterinarian,Shenyang Agricultural University,Shenyang,110161);The Molecular Biology Characteristic of The Viral to Destroy Immune System of Swines[J];Jilin Animal Science and Veterinary Medicine;2006-02
5 Wei Gounghe Zhou Renhui Tang Fashu;THE EXTRACTION OF GOOSE PARVOVIRUS DNA THROUGR IMMUNE COMPLEX METHOD[J];Journal of Sichuan Institute of Animal Husbandry and Veterinry Medicine;2001-02
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1 YANG Song - Tao XIA Xian - Zhu QIAO Jun WANG Tie - Cheng CHANG Shuang HUANG Geng(Institute of Military Veterinary, Academy of Military Medical Science of PLA, Changchun 130062);EXPRESSION OF VP2 GENE OF FELINE PANLEUKOPENIA VIRUS TIGER ISOLATEIN PICHIA PASTORIS YEAST[A];[C];2005
【Co-references】
Chinese Journal Full-text Database 10 Hits
1 XU Guang-zhi,ZHANG Zhi-fang,QIAN Guang-xing,HUANG Ke-wei,GUO Xi-jie (Sericultural Research Institute,Chinese Academy of Agricultural SSilkworm Biotechnology,Ministry of Agriculture.Zhenjiang 212018,China);Cloning of the Major Structural Protein Gene of Densovirus (Zhenjiang Isolate) in Silkworm,Bombyx mori,and Its Expression in Escherichia coli[J];Chinese Journal of Virology;2004-03
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3 YAN Xinpei 1 ZHONG Boxiong 1 XU Mengkui 1 GUO Dingguo 2 YAO Guohua 1( 1Laboratory of Molecular Biology of Silkworm and Honeybee, College of Animal Science, Zhejiang University, Hangzhou 310029; 2Silkworm Breeding Reproduction Institute of Guangdong Province, Guangzhou 510640);The Relation Between the Protein Composition of Posterior Silkglands in the Fifth Instar Larva of Silkworm and Cocoon Shell Weight[J];Acta Sericologica Sinica;2003-04
4 YAN Xinpei 1 ZHONG Boxiong 1 CAO Jiashu 2 XU Mengkui 1 SHEN Feiying 1 YAO Guohua 1( 1Laboratory of Molecular Biology of Silkworm and Honeybee, College of Animal Science, Zhejiang University, Hangzhou 310029; 2Laboratory of Cell and Molecular Biology, College of Agriculture & Biotechnology, Zhejiang University, Hangzhou 310029);Establishment of 2D-PAGE Protein Patterns of Silkworm Embryo During Incubating Stage[J];Acta Sericologica Sinica;2004-01
5 YAO Guohua ZHONG Boxiong YAN Xinpei SHEN Feiying CHEN Qilong ZHOU Li TONG Xiaofen(Department of Bioresource Science,College of Animal Science,Zhejiang University,Hangzhou 310029);Analysis of Characterization of the Key Proteins Associated Embryonic Development of the Silkworm,Bombyx mori[J];Acta Sericologica Sinica;2004-04
6 WU Weicheng~1,2 ZHONG Boxiong~(1*) MENG Zhiqi~2 CHEN Jin’e~1,2YAN Xinpei~1 YE Jian~1 SHEN Feiying~1(~1 Laboratory of Molecular Biology of Silkworm and Honeybee, Department of Bioresource Science, College of Animal Science, Zhejiang University, Hangzhou 310029,China;~2 Laboratory of Molecular Biology of Insect, Zhejiang Academy of Agricultural Sciences, Hangzhou 310021,China);Composition Analysis of Protein From Posterior Silkgland of Silkworm Bombyx mori Between Larvae of 4~(th) Molting Stage and the 5~(th) Instar Stage[J];Acta Sericologica Sinica;2005-03
7 YE Jian~1 ZHONG Boxiong~(1*) LIN Jianrong~2 YAN Haiyan~1 LIANG Jianshe~3SU Songkun~1 XU Haisheng~1(~1Department of Bioresource Science, College of Animal Sciences, Zhejiang University, Hangzhou 310029, Chian;~2Department of Sericulture Science, College of Animal Science,South China Agricultural University, Guangzhou 510642, China;~3Biochemistry Co. Ltd. of Zhejiang University, Hangzhou 310004, China);The Changes of the Expressed Proteins From Temperature Sensitive Silkworm, Bombyx mori, Breed During Embryo Development[J];Acta Sericologica Sinica;2005-03
8 SHEN Fei-Ying~(1) ZHONG Bo-Xiong~(1*) LOU Chen-Fu~(1) HONG Bo~(1)JIANG Zhen-Dong SU Song-Kun~(1) LIANG Jian-She~(2) XU Hai-Sheng~(1) (~(1)College of Animal Science,Zhejiang University,Hangzhou 310029,China;~(2)Biochemistry Co.Ltd.of Zhejiang University,Hangzhou 310004,China);Investigation on Protein Variety in Middle Silkgland Cells of Silkworm,Bombyx mori,During Fifth Instar Stage[J];Science of Sericulture;2006-01
9 LU Hua-Yun~(2) YE Jian~(1) LI Jian-Ying~(1) ZHONG Bo-Xiong~(1*) (~(1) Laboratory of Molecular Biology of Silkworm and Honeybee,College of Animal Science,Zhejiang University,Hangzhou 310029,China;~(2) Hangzhou Popularization Station for Fine Breed of Special Local Products,Hangzhou 310002,China);Analysis of 2D-PAGE Patterns of Proteins in Posterior Silkgland From Different Silkworm Varieties on 4~(th) Day in 5~(th) Instar[J];Science of Sericulture;2006-01
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【Secondary References】
Chinese Journal Full-text Database 1 Hits
1 QIU Zhi-Yong1,2 LI Mu-Wang1,2 SHEN Xing-Jia1,2 GUO Xi-Jie1,2*(1The Sericultural Research Institute,Chinese Academy of Agricultural Sciences,Key Laboratory ofSilkworm Biotechnology,Ministry of Agriculture of China,Zhenjiang Jiangsu 212018,China; 2Jiangsu University of Science and Technology,Zhenjiang Jiangsu 212003,China);Proteomic Changes of Midgut and Hemolymph of Silkworm in Advanced Stage of Infection by Bombyx mori Densovirus(Zhenjiang Strain)[J];Science of Sericulture;2008-04
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