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Studies on flavonoids from allium mongolium regel effects to non-specific immunity function in mice

Zhao Chunyan,Ao Changjin,Zhang Xingfu  
Is this paper,Kunming mice were used to study the effect of flavonoids separated and purified from allium mongolium regel on non-specific immunity function in body.480 [weight (20±2) g] pureblooded Kongming mice,which were divided randomly into four groups and each group 120 (half female and half male),were raised in different cages which were named control group,75.36mg/kg·BW·d Allium mongolium Regel supplementation group,75.36 mg/(kg BW·d) flavonoid extract supplementation group,75.36 mg/(kg BW·d) flavonoids purification supplementation group.Preparatory experimental period lasted for 5 days and the formal experimental period lasted for 14 days.After two slaughters being done during the formal experimental period,two slaughter experiment were conducted,the blood was collected and serum was isolated ,and live thymus and spleen was dissected and weighed.The result show that,the spleen index of experiment groups were higher than that of control group,but the difference was not significant (P0.05).The thymus index of flavonoids purification group was higher than that of other groups (P0.05).The content of ACP in serum of flavonoids purification group was higher than that of other groups (P0.05);The carbon clearance index of experiment groups was higher than that of control group,but the difference was not significant (P0.05).The phagocytic index and lysozyme content in serum of flavonoids purification group were higher than other groups(P0.05).
【Fund】: 国家自然科学基金(编号:30760173)
【CateGory Index】: S54
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