Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Journal of Chongqing University(Natural Science Edition)》 2005-07
Add to Favorite Get Latest Update

Experimental Study of Energy Controllable Steep Pulse in the Treatment of Rat with Subcutaoneous Transplantive Tumor

LUO Xiao-dong 1 , HU Li-na 1 , SUN Cai-xin 2 , YAO Chen-guo 2 , XIONG Lan 2 , MI Yan 2 , WANG Shi-bin 2 (1.Department of Obstetrics and Gynecology, the Second Affilate Hospital, Chongqing University of Medical Science, Chongqing 400010, China; 2. Key Laboratory of High Voltage Engineering and Electrical New Technology Under the State Ministry of Education,Chongqing University, Chongqing 400030, China)  
To investigate the effects of immune function of energy controllable steep pulse on the transplanted tumor in rat. Tumor size were measured before and after treatment to evaluate the reaction of the treatment. After two weeks of treatment, MTT methods were used to observe the lymphocytes proliferation and the natural killer cells(NK) activity. TNF-α activities was measured by ELISA. The result shows that the growth of the tumor is significantly inhibited in ECSP therapy group as compared with the controls. It is founded that the Lymphocytes proliferation, the natural killer cells(NK) activity and TNF-α activities in ECSP therapy group is similar to that of the normal control group, there is no obvious difference(P=0.953, P=0.130, P=0.080),but these parameters are markedly higherly than the that of the control group (P0.05,P0.05,P0.05). ECSP can inhibit the growth of the tumor and induce the host immune reaction of anti-tumor efficiently and improve the immune activity of lymphocyte and macrophage in rats with tumor.
【Fund】: 国家自然科学基金资助项目(30271484)
【CateGory Index】: R73-36
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
【References】
Chinese Journal Full-text Database 1 Hits
1 LI Shi-fen, ZHAO Yan, HU Qi(Center for Hygienic Analysis and Detection, School of public health, NJMU, Nanjing 210029, China);Effects of polyrhachis vicina roger on immune modulation in mice[J];Acta Academiae Medicinae Nanjing;2005-12
【Citations】
Chinese Journal Full-text Database 5 Hits
1 YAO Chen-guo, SUN Cai-xin, XIONG Lan, MI Yan, WANG Shi-bin Under the State Ministry of Education, Chongqing University, Chongqing 400030, China);Irreversible Electrical Breakdown of Malignant Tumor Cell Under Steep Pulsed Electric Fields[J];Journal of Chongqing University(Natural Science Edition);2004-06
2 HU Ya, HU Li na, MI Yan, YAO Cheng guo, XIONG Lan, SUN Cai xin (Department of Obstetrics and Gynecology, Second Affiliated Hospital, Chongqing University of Medical Sciences, Chongqing 400010, China);Effects of the energy controllable steep pulses on human ovarian carcinoma cell in vitro[J];Acta Academiae Medicinae Militaris Tertiae;2003-16
3 Yao Chenguo 1 Sun Caixin 1 Xiong Lan 1 Mi Yan 1 Liao Ruijin 1 Hu Lina 2 Hu Ya 21 (College of Electrical Engineering, Chongqing University, Chongqing,400044,China)2 (Second Affiliated Hospital, Chongqing University of Medical Sciences, Chongqing,400061,China);Effect of Steep Pulsed Electric Fields on Survival of Tumour-bearing Mice[J];Journal of Biomedical Engineering;2004-03
4 He Jinsheng;Li Ruizhu;Zong Tingyi( Department of Microbiology,Anhui Medical University,Hefei 230032);INVESTIGATION OF NK CELL ACTIVITY MEASUREMENT[J];CHINESE JOURNAL OF IMMUNOLOGY;1996-06
5 LI Da - qiang,et al (Department of Obstetrics and Gynecology, Second College of Clinical Medicine, Chongqing Medical University);Observation of injuring effect of energy controllable steep pulses on tumor tissues cut from the hosts ' body[J];Acta Universitatis Scientiae Medicinae;2001-04
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 WU Xiao-juan1, YAO Zhen-wei1,TANG Jun-ying1, YAO Chen-guo2, SUN Cai-xin2 (1Department of Gynecology and Obstetrics, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016; 2 Key Laboratory of High Voltage and Electrical New Technology of Ministry of Education, College of Electrical Engineering, Chongqing University, Chongqing 400044, China);Growth inhibition and apoptosis induction of nanosecond steep pulse on human ovarian carcinoma cell line SKOV_3[J];Acta Academiae Medicinae Militaris Tertiae;2007-17
2 Shen Jie,Guo Lianying,Shi Guangxia,et al [WT5BX]Institute for Cancer Biotherapy,Dalian Medical University,Dalian,China [WT5HZ];Effects of elemene combo-tumor cell vaccine immunotherapy on tumor growth and cytotoxicity[J];JOURNAL OF DALIAN MEDICAL UNIVERSITY;2000-01
3 WANG Xu, LIANG Wei, ZHANG Meng jie, CHEN Yong qing (Department of Microbiology and Microbial Biotechnology);Isolation of the Ribosomal 16 ku Component of the Bacteria Serratia Odorifera and Its Effects on Tumor-inhibiting and Immune Enhancement in Vivo[J];JOURNAL OF FUDAN UNIVERSITY;1999-05
4 WU Jun1, WANG Xiao-huai1, YANG Tai-cheng2, XIAN hang2 (1Department of Oncology, 2lnstitute of Molecular Oncology, General Hospital of Guangzhou Command, Guangzhou 510010, China);The detection of phytohemagglutinin-lymphokine activated killer cells' in vitro antitumor action with MTT colorimetry[J];Journal of First Military Medical University;2001-11
5 LI Yan-Wei1, JIANG-Bo2, TONG Xiang-Shan 1* (1. College of Life Science, Jilin University, Changchun 130023, China; 2. Changchun Institute of Biological Products, Changchun 130021, China);Purification and Function Research of Active Peptide from Pig Blood Hydrolyzed by Trypsin[J];Chemical Research In Chinese Universities;2005-01
6 YU Jin-mei 1,XIONG Zheng-ai 1,LING Xiao-juan 1,SUN Cai-xin 2,YAO Chen-guo 2,HONG Chuan 2,MO Deng-bin2,MI Yan 2,WANG Shi-bin 2(1Department of Obstetrics and Gynecology,The Second Affiliated Hospital,Chongqing University of Medical Sciences,Chongqing 400010;2Key Lab of High Voltage Engineering and Electrical New Technology of Ministry of Education,Chongqing University,Chongqing 400044,China);Metrological study on damaging effect of steep pulsed electric field on fresh excised calf liver[J];Acta Academiae Medicinae Militaris Tertiae;2006-24
7 WANG Ping-ling 1, HU Li-na 1, LI Cong 1, SUN Cai-xin 2, MI Yan 2, WANG SHI-bin 2, YAO Cheng-guo 2 ( 1Department of Obstetrics and Gynecology, The Second Affiliated Hospital, Chongqing University of Medical Science, Chongqing 400016; 2Key Lab of High Voltage Engineering and Electrical New Technology, Ministry of Education, Chongqing 400044, China);Experimental study of energy controllable steep pulses and RNA interference targeting H-ras gene on inhibiting growth of xenografted tumor of ovarian cancer cells[J];Acta Academiae Medicinae Militaris Tertiae;2005-06
8 LI Jun1, YANG Xiao-Jun1, HU Li-Na1, SUN Cai-Xin2, YAO Chen-Guo2 1. Department of Gynecology and Obstetrics, The Second Affiliated Hospital, Chongqing University of Medical Science, Chongqing, 400010, P. R. China 2. Key Laboratory of Voltage Engineering and Electrical New Technology of Ministry of Education, Chongqing University, Chongqing, 400044, P. R. China;Impacts of Steep Pulsed Electric Fields on Lymphatic Capillaries in VX_2 Implanted Breast Cancer in Rabbits[J];Chinese Journal of Cancer;2006-02
9 YAO Chenguo,SUN Caixin,MI Yan,LI Chengxiang(Key Laboratory of High Voltage and Electrical New Technology of Ministry of Education,College of Electrical Engineering,Chongqing University,Chongqing 400044,China);Progress in Research of Irreversible Electrical Breakdown of Steep Pulse for Tumor Treatment and Its Key Techniques[J];High Voltage Engineering;2007-02
10 LI Chengxiang1,YAO Chenguo1,MI Yan1,SUN Caixin1,XIONG Zheng'ai2,LING Xiaojuan2,GU Huayan2(1.Key Laboratory of High Voltage and Electrical New Technology of Ministry of Education,Chongqing University,Chongqing 400044,China;2.Second Affiliated Hospital,Chongqing Medical Science University,Chongqing 400061,China);Dosimetry Study on Irreversible Electrical Breakdown of Rabbit Liver Tissue Under Steep Pulsed Electric Field[J];High Voltage Engineering;2007-02
China Proceedings of conference Full-text Database 1 Hits
1 Zhang Hui, Wang Guoxiong, Shen Chuanlai, Xiang Longsheng, et al. (Department of Environmental Health, Public Health School, South east University, Nanjing 210009);Investigation on the Immunological Index for Cell-mediated Immunity in Cooking Workers[A];[C];2005
【Co-references】
Chinese Journal Full-text Database 10 Hits
1 Xiao Huajuan, Yan Ping, Zhang Shichang( Electrical Research Institute of China Science Academy, Beijing 100800, China);THE MECHANISM AND RESEARCH PROGRESS OF THE INTRACELLULAR ELECTRO-MANIPULATION APPLIED WITH NANOSECOND PULSED ELECTRICAL FIELD[J];High Voltage Engineering;2004-04
2 HU Ya~(1), HU Li-na~(2), MI Yan~(3), YAO Cheng-guo~(3), XIONG Lan~(3), SUN Cai-xin~(2) ( ~(1)Department of Obstetrics and Gynecology, No. 324 Hospital of PLA, Chongqing 400020; ~(2)Department of Obstetrics and Gynecology, The Second Affiliated Hospital of Huaxi Medical College, Sichuan University, Chengdu 610041; ~( 3)College of Electrical Engineering, Chongqing University, Chongqing 400044, China);Lethal effects of energy controllable steep pulses on U_(14) cervical cancer in mice[J];Acta Academiae Medicinae Militaris Tertiae;2005-17
3 HU Ya, HU Li na, MI Yan, YAO Cheng guo, XIONG Lan, SUN Cai xin (Department of Obstetrics and Gynecology, Second Affiliated Hospital, Chongqing University of Medical Sciences, Chongqing 400010, China);Effects of the energy controllable steep pulses on human ovarian carcinoma cell in vitro[J];Acta Academiae Medicinae Militaris Tertiae;2003-16
4 LI Feng, ZHOU Yuan( Department of Chemistry, College of Chemistry and Chemical Engineering, Hunan Normal University, Changsha410006, China; Department of Pharmacology, Medical College, Hunan Normal University, Changsha 410006,China);Ant's specific effects of anti-aging and therapeutics[J];Immunological Journal;2004-S1
5 Cao Xiaozhe, Zhao Meilan, Wang Dewen. Institute of Radiation Medicine, Academy of Military Medical Sciences, Beijing 100850;INFLUENCE OF EMP IRRADIATION ON LDH, AST, CHE, K+ AND Na+ EN SUPERNATANT OF CULTURED RAT PI- TUITARY CELLS[J];Medical Journal of Chinese People's Liberation Army;2002-10
6 SUN Cai-xin 1 , YAO Chen-guo 1 , XIONG Lan 1 , MI Yan 1 , LIAO Rui-jin 1 , HU Li-na 2 , HU Ya 2 (1.Key Laboratory of High Voltage Engineering and Electrical New Technology,Ministry of Education,Chongqing 400044,China;2.Second Affiliated Hospital,Chongqing University of Medical Science,Chongqing 400010,China);KILLING EFFECTS OF PULSED ELECTRIC FIELDS ON MALIGNANT TUMOR CELL[J];Acta Biophysica Sinica;2002-04
7 YANG Xiaojun 1,HU Lina 1,LI Jun 1,SUN Caixin 2,et al(1.The Second Affiliate Hospital,Chongqing University of Medical Science,Chongqing 400016,China;2.Key Laboratory of VoltageEngineering and Electrical New Technology of Ministry of Education,Chongqing University,Chongqing 400044,China);Experimental Study of DNA Strand Breaks of SKOV 3 Induced by Low Energy Steep Pulse[J];Journal of Practical Obstetrics and Gynecology;2004-06
8 Yao Chenguo 1 Sun Caixin 1 Xiong Lan 1 Mi Yan 1 Liao Ruijin 1 Hu Lina 2 Hu Ya 21 (College of Electrical Engineering, Chongqing University, Chongqing,400044,China)2 (Second Affiliated Hospital, Chongqing University of Medical Sciences, Chongqing,400061,China);Effect of Steep Pulsed Electric Fields on Survival of Tumour-bearing Mice[J];Journal of Biomedical Engineering;2004-03
9 Yao Chenguo 1 Sun Caixin 1 Mi Yan 1 Xiong Lan 1 Hu Lina 2 Hu Ya 2 1 (Key Lab of High Voltage Engineering and Electrical New Technology,Ministry of Education,Chongqing University,Chongqing 400044,China) 2 (Second Affiliated Hospital,Chongqing University of Medical Sciences,Chongqing 400044,China);Effects of Steep Pulsed Electric Fields on Cancer Cell Proliferation and Cell Cycle[J];Journal of Biomedical Engineering;2004-04
10 HU Ya1, HU Li-na2, XIONG Lan3,et al(1.Department of Obstetrics and Gynecology, the No.324 Hospital of the Chinese People' sLiberation Army, Chongqing,400020,China; 2.Department of Obstetrics and Gynecology,Second Affiliated Hospital, Chongqing Medical University, Chongqing,400010,China;3.College of Electrical Engineering, Chongqing University, Chongqing,400044,China);Effect of energy controllable steep pulses on survival of tumor-bearing mice[J];Journal of Practical Oncology;2005-04
【Secondary References】
Chinese Journal Full-text Database 1 Hits
1 Xue Chang-yong, Zheng Zi-xin, Zhang Rong-xin, Liu Ying-hua, Zhang Yue-hong, Jing Hong-jiang Department of Nutrition, General Hospital of Chinese PLA, Beijing 100853, China;Active effect of alcohol extracts from Polyrhachis Vicina Roger on improving the glucose metabolism in KKAy mice with diabetes mellitus[J];Chinese Journal of Clinical Rehabilitation;2006-43
【Secondary Citations】
Chinese Journal Full-text Database 8 Hits
1 MI Yan 1, SUN Cai? xin 1, YAO Chen? guo 1, XIONG Lan 1, HU Ya 2, HU Li? na 2 (1. The Key Laboratory of High Voltage Engineering and Electrical New Technology, Ministry of Education, Chongqing University, Chongqing 400044, China; 2. The Second Affiliated Hospital, Chongqing University of Medical Sciences, Chongqing 400010, China);Development and Application of Steep Pulse Apparatus for Tumor Treatment[J];Journal of Chongqing University(Natural Science Edition);2003-02
2 SUN Cai-xin 1 , YAO Chen-guo 1 , XIONG Lan 1 , MI Yan 1 , LIAO Rui-jin 1 , HU Li-na 2 , HU Ya 2 (1.Key Laboratory of High Voltage Engineering and Electrical New Technology,Ministry of Education,Chongqing 400044,China;2.Second Affiliated Hospital,Chongqing University of Medical Science,Chongqing 400010,China);KILLING EFFECTS OF PULSED ELECTRIC FIELDS ON MALIGNANT TUMOR CELL[J];Acta Biophysica Sinica;2002-04
3 Zhang Jin-zhu Kong Ke-jian (Dept. of Cell Biophysics Institute of Biophysics, Academia Sinica.) Lu Qi-wu Dong Ren-jie (Technical Center of Analyses and Measurements Institute of Biophysica, Academia Sinica.);FREEZE-FRACTURING STUDIES ON HUMAN ERYTHROCYTE MEMBRANES EFFECTED BY EXTERNAL PULSED ELECTRICAL FIELD[J];Acta Biologiae Experimentalis Sinica;1994-02
4 Yu Tinghe,Peng Mingli,Wang Zhibiao Institute of Ultrasound Engineering in Medicine,Chongqing Medical University Chongqing 400016;A Stereological Study on the Mitochondria in Ovarian Carcinoma Cells Damaged by Ultrasound[J];CHINESE JOURNAL OF ULTRASOUND IN MEDICINE;2000-04
5 Niu Zhong-qi(Xidian University,Xi'an);THE SELF-ELECTRIC FIELD STRESS EXERTED ON CELL MEMBRANE[J];CHINESE JOURNAL OF BIOMEDICAL ENGINEERING;1994-01
6 LI Da - qiang,et al (Department of Obstetrics and Gynecology, Second College of Clinical Medicine, Chongqing Medical University);Observation of injuring effect of energy controllable steep pulses on tumor tissues cut from the hosts ' body[J];Acta Universitatis Scientiae Medicinae;2001-04
7 Zhu Fansan;Chen Baihao;Lin Jiarui;Xie Zeping(Huazhong University of Science & Technology,Wuhan);EXPERIMENTAL STUDIES OF R-WAVE SYNCHRONIEINGELECTRIC PULSES TREATMENT FOR CANCER[J];CHINESE JOURNAL OF BIOMEDICAL ENGINEERING;1995-04
8 Tian Zhigang, Zhang Jianhua (Shangdong Academy of Medical Sciences, Shandong Cancer Biotherapy Center, Jinan, 250001);Application of MTT Colorimetric Assay in Research of Cytokine Activity and Cytotoxicity of Killer Cells[J];Chinese Journal of Cancer Biotherapy;1994-01
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved