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《Fujian Analysis & Testing》 2012-06
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Electrochemical determination of Tetrahydropalmatine at a carbon nanotube modified glassy carbon electrode

Chen Xian*,Liu Ting,Xu Xiao-ping,Chen Guo-nan(College of Chemistry and Chemical Engineering,Fuzhou University,Fuzhou,Fujian 350108,China)  
The electrochemical oxidation of tetrahydropalmatine(THP)at a carbon nanotube modified glassy carbon electrode(CNT/GCE)has been investigated.In the Michaelis.buffer solution(pH6.20),one well-defined oxidation peak of THP was obtained,and the peak potential was 0.90V(vs.Ag/AgCl).The peak current was proportional to the concentration of THP over the range of 8.0×10-7~5.0×10-5mol/L by Square Wave Voltammetry.The detection limit was 3.0×10-7mol/L.Furthermore,a quantitative analysis of THP in two real samples was established based on the electrochemistry behavior of THP.The method was applied to the determination of THP in Chinese herb and medicine with satisfactory results.
【Key Words】: Tetrahydropalmatine Carbon nanotube modified glassy carbon electrode Square wave voltammetry
【Fund】: 国家自然科学基金资助项目(41076059);; 教育部博士点基金资助项目(20103514110002)
【CateGory Index】: O657.1;R286.0
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