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《Journal of Fujian Medical University》 2006-05
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The Relationship between Microalbuminuria and Carotid Intima-media Thickness in Type 2 Diabetic Patients

Su Yana,Shi YaxiongThe Affiliated Second Hospital,Fujian Medical University,Quanzhou,362000,China  
Objective To evaluate the relationship between microalbuminuria and carotid atherosclerosis in type 2 diabetic patients.Methods Urinary albumin excretion rate(UAER) and carotid intima-media thickness(C-IMT) were measured in 74 cases of type 2 diabetic patients.The association between UAER and C-IMT were studied.Results C-IMT in subjects with microalbuminuria and normalbuminura were(1.15±0.38)mm and(0.89±0.24)mm respectively(P0.05). Subjects with microalbuminuria have higher age,BMI,systolic blood pressure(SBP),diastolic blood pressure(DBP) and pulse pressure(PP)(P0.05).UAER was positively correlated with C-IMT,age,BMI,SBP,DBP and PP,with the correlation coefficient 0.28,0.35,0.25,0.36,0.25 and 0.33,respectively(P0.05).After adjustment of age,blood pressure and BMI,UAER was associated with C-IMT only in hypertensive group,with the correlation coefficient 0.44(P(0.05)).Conclusion Microalbuminuria can imply subclinical atherosclerosis to some extent.
【CateGory Index】: R587.1;R543.4
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