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《Journal of Fujian Medical University》 2010-02
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Anti-Tumor Activity of Extracts of Bidens bipinnata L in vitro

LIN Liqing,LIN Xinhua,HUANG Liying,ZHENG Yanjie,LI XiaoyanSchool of Pharmacy,Fujian Medical University,Fuzhou 350004,China  
Objective To investigate the anti-tumor effect of the extracts of Bidens bipinnata L in vitro.Methods Using different concentration of the four kind extracts,control group of masculine,control blank group,the cytotoxic effects of the four extracts of Bidens bipinnata L on HepG2 and K562 were tested by MTT assay.The tumor cell lines were cultured in vitro.Results The extracts of Bidens bipinnata L significantly arrested the growth of the two malignant tumor cells in vitro.IC50 of these cells reached 9.17 μg/ mL and 12.74 μg/mL,respectively when exposed to the extracts from chloroform for 48 hours.Conclusion The chloroform extracts of Bidens bipinnata L have obvious anti-tumor activity in vitro.
【Fund】: 国家自然科学基金(20675015);; 福建省卫生厅青年基金(2006111)
【CateGory Index】: R285
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