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《Fujian Meidical Journal》 2001-04
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Study of diagnostic value of simultaneous detection of(TSGF、NSEand CA125)of three tumor markers in patients with lung cancer

Gu Yan Hong  
Objective\ To study diagnostic value of simultaneous detection of three tumor markers(tumor specific growth factor,TSGF,neuron specific enolaes,NSE:carbohydrate chain antigen 125,CA 125 )in patients with lung cancer.Methods TSGF was measured by septometer method.NSE and CA125 were measured by Enzymelinkde immenosorbert assay.Results The level of three tumor marker in lung cancer group(n=65)was higher than that of benign lung disease group(n=67)and control group(n=73)(P0 01) The sensitivity of TSGF to lung cancer was 86 9% and specificity was 91 1%;The sensitivity of NSE was 46 17% and specificity was 93 23%;The sensitivity of CA 125 was 56 43% and specificity was 84 72% By three positive indexes in three tumor markers as diagnostic base on lung cancer,the positive rate was 41 35% But no positive case was found in benign lung diseases group and control group Conclusion The three indexes have diagnostic value to lung cancer and simultaneous detection has obvious complementarity And it can significantly improve the sensitivity and specificity in diagnosis of lung cancer
【CateGory Index】: R734.2
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