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《Fujian Meidical Journal》 2002-02
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Drug Sensitivity on Extended-spectrum β-lactamases Producing Clinical Strains in FuZhou

Lin Qingan,Lai Guoxiang,Huang Lianghu  
Objective To investigate the drug sensitivity of extended spectrum β lactamases(ESBLs) producing Klebsiella pneumoniae and Escherichia coli to 14 antibiotics in Fuzhou.Methods Phenotypic confirmatory test was used to detect ESBLs in 426 strains of Klebsiella pneumoniae and Escherichia coli ;Kirby Bauer agar diffusion method was used to judge drug sensitivity.Results 33 33% of strains were considered ESBLs producers by phenotypic confirmatory test.The resistant rates of ESBLs producing strains to most antibiotics were high.The resistant rates of Imipinem,Cefoperazone/Sulbactam,Piperacillin/Tazobactam and Cefmetazole to ESBLs producing strains were the lowest.Conclusions The prevalence of ESBLs producing strains in Fuzhou was high;The resistant rates of ESBLs producing strains to most antibiotics were high.Imipinem,Cefoperazone/Sulbactam,Piperacillin/Tazobactam and Cefmetazole were the effective antibiotics to infections caused by ESBLs producing strains.
【CateGory Index】: R446.5
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