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《Fujian Medical Journal》 2004-03
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Researchering the mechanism of GLP’s hypoglycem

Zhang Lingzhi,Feng Lei.Zheng Jiang Medical School,Hangzhou 310053,China  
Objective ]observing the hypoglycemic effect of GLP,and its action mechanism is also preliminary explored.observing the hypoglycemic effect of GLP,and its action mechanism is also preliminary explored. establishing the SD rats model and divided them into 5 groups randomly and ig different dose with GLP,measuring blood sugar,insulin,liver glucokinase,liver glucogen. GLP decreases blood sugar,increases insulin secretion,recover the B cells and improve the liver glucokinase activity.[Conclusion] GLP has dramatic hypoglycemic activity,it can promote insulin secretion through recovery the B cells which were damaged by alloxan and improve the liver glucokinase activity.
【Fund】: 浙江省教育厅科研基金资助
【CateGory Index】: R285
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