Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Rheumatism and Arthritis》 2013-12
Add to Favorite Get Latest Update

Changes of Heart Function of 140 Cases with Ankylosing Spondylitis and Relative Analysis

Qi Ya-jun;Liu Jian;Cao Yun-xiang;Sun Yue;Wang Fang;Ye Wen-fang;  
Objective:To study the changes of heart function of patients with ankylosing spondylitis and analyze their correlativity with other indexes.Methods:Changes of heart function of 140 cases with ankylosing spondylitis were detected by ultrasonic cardiogram (UCG)and compared with those of 30 cases in the normal control group,observing their clinical symptoms,signs,laboratory indexes and their correlativity with parameters of cardiac function and exploring the mechanism.Results: ① The abnormal rate of the ankylosing spondylitis group was 33.56% by UCG,while that of the normal control group was 9.99%,the difference being statistically significant (P0.01). ② The blood stream peak of the late diastole (peak A)in the patients with ankylosing spondylitis increased significantly (P0.01); the blood stream peak of the early diastole (peak E),the ejection fraction (EF) and the ratio of E/A decreased significantly(P0.01). ③ The Spearman correlation analysis showed that there were positive correlations respectively between the heart function parameter peak E and interleukin- 10,and between peak A and palpitations (P0.05 or P0.01).There were negative correlations respectively between peak E and duration of disease,loss of appetite,few words due to deficiency of qi,abdominal distention after eating,loose stool,blood platelet count,uric acid,immunoglobulin G,erythrocyte sedimentation rate and C-reactive protein,between E/A ratio and the course of disease,loss of appetite,few words due to deficiency of qi,abdominal distention after eating,loose stool,a- acidoglycoprotein and interleukin-17,between ejection fraction (EF)and the course,palpitations,fatigue,a bdominal distention after eating,C3,and between FS and few words due to deficiency of qi and triglycerid (eP0.05 or p0.01).Conclusion:The cardiac function of patients with ankylosing spondylitis decreased,manifesting on the aspects of the increase of peak A and the decrease of peak E,ejection fraction (EF)and the ratio of E/A,and being relative with integrals of symptoms and signs and laboratory indexes.The mechanism of cardiac function decline in patients with ankylosing spondylitis might be myocardial damage due to its immune function disorder and cytokine imbalance.
【Fund】: 国家中医药重点学科中医痹病学建设项目—国中医药发〔2009〕30号;; 安徽省科技厅科研计划项目(11010402170);; 安徽中医内科应用基础与开发研究省级实验室项目(科条〔2008〕150号);; 安徽中医学院科技创新团队项目(2010TD005)
【CateGory Index】: R593.23
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
【Citations】
Chinese Journal Full-text Database 1 Hits
1 LIU Jian,CAO Yun-xiang,ZHU Yan(The First Affiliated Hospital of Anhui College of TCM,Hefei 230031,China);Cardiac function changes of aged rheumatoid arthritis and the correlation[J];China Journal of Traditional Chinese Medicine and Pharmacy;2011-04
【Co-citations】
Chinese Journal Full-text Database 7 Hits
1 Jin Jianwei TCM Hospital of Tonglu County, Zhejiang Province(311500);Analysis to the Cause of Wrong Diagnosis of 2 Cases of Ankylosing Spondylitis[J];Journal of Zhejiang University of Traditional Chinese Medicine;2007-02
2 Zhao Zhiyou,Wu Yajun,Wang Xinchang The Departmeng of TCM,No.117 Hospital of PLA,Hangzhou,Zhejiang(310013);Clincal Study on Ankylosing Spondylitis with Playing Treatment According to Diagnosis and DMARDs[J];Journal of Zhejiang Chinese Medical University;2011-04
3 LOU Yu-qian(Henan Hospital of Rheumatism,Henan Rheumatism Research Institute,Zhengzhou 450045,China);The standardized research of nomenclature and classification of rheumatism[J];China Journal of Traditional Chinese Medicine and Pharmacy;2008-09
4 Zeng Yingyu,Huang Chenghui(Division of Rheumatology,SecondAffiliated Hospital of Guangzhou Medical College,Guangzhou 510260,China);Clinical Analysis of Ankylosing Spondylitis Characteristics in 130 Cases[J];Chinese Journal of Medicinal Guide;2012-05
5 Yan Xiao-ping,Tao Qing-wen,Kong Wei-ping,Wang Jian-ming,Xu Yuan,Wang Hao,Zhang Ying-ze, Zhu Jun-ling,Luo Wei,Lu Ping,Jin Di-er,Ma Xiao,Zhang Nan,Yan Jue,Zhang Wei,Ju Hai,Peng Jian-ying,Yi Jing-yang,Qiu Xin-ping;Comprehensive Therapy of Invigorating the Kidney and Du meridian on Ankylosing Spondylitis:A Series Study of Clinical and Experimental Research[J];Rheumatism and Arthritis;2012-03
6 Seol Sang-ho,WANG Hao,YAN Xiao-ping(Department of TCM Rheumatism,China-Japan Friendship Hospital,Beijing 100029);Bushenqiangdu Formula for curing ankylosing spondylitis(syndrome of kidney deficiency,Du meridian cold and blood stasis)[J];Journal of Beijing University of Traditional Chinese Medicine(Clinical Medicine);2009-02
7 TAO Qing-wen,XU Yuan,KONG Wei-ping,WANG Jian-ming,YAN Xiao-ping(China-Japan Friendship Hospital,Beijing 100029);Clinical Research of Pattern/Syndrome Differentiation and Treatment of Ankylosing Spondylitis Based on the Experiences of Distinguished Veteran Doctor of Traditional Chinese Medicine[J];World Journal of Integrated Traditional and Western Medicine;2013-07
【Secondary Citations】
Chinese Journal Full-text Database 3 Hits
1 LIU Jian Tutor:Professor HAN Ming xian (The First Affiliated Hospital ,Anhui College of TCM, Anhui Hefei 230031,China);DIFFERENTIATION TREATMENT FOR AGED RHEUMATOID ARTHRITIS[J];Journal of Anhui Traditional Chinese Medical College;2001-06
2 LIU Jian,ZONG Rui-kai,YU Xue-fang,WANG Yuan(First Hospital Affiliated to College Anhui of TCM,Hefei 230031,China);Effects of Xinfeng Capsule on platelet parameters,p-select,platelet ultrastructure and its therapeutic effect on rheumatoid arthritis patients in active phase[J];China Journal of Traditional Chinese Medicine and Pharmacy;2008-12
3 CHEN Rui-lian,LIU Jian,PAN Yu-zhen,ZHU Huai-min(Rheumatism Department,First Affiliated Hospital of Anhui College of TCM,Hefei 230031,China);The changes and significance of CD4~+CD25~+CD127~(lo) regulatory T cells in patients with rhrumatoid arthritis[J];Chinese Journal of Clinical Healthcare;2008-06
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved