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《Chinese Journal of Rheumatology》 2001-03
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Mixture injection of Chinese herbal drugs in the treatment of BXSB mouse systemic lupus erythematosus

ZHAO Guoqing ,XU Shizheng,LI Suping,et al. Department of Dermatology,People′s Hospital of Wchan University,Wuhan 430060,China.  
Objective To investigate the effect of the mixture injection of ruberbs and astrugulars in the treatment of SLE like BXSB mice.Methods Fifteen male and six female BXSB mice at the age of three months were randomly divided into 3 groups:group A was Chinese herb group treated with mixture injection of rhuberb and radix astragali;group B was dexamethasone group;group C was normal saline group.Three groups of BXSB mice were intra abdominal injection every day for six weeks.The levels of proteinuria in different groups of BXSB mice were measured by spectrophotometry.The titers of anti nuclear antibodies (ANA) and the depositions of immunoglobulins in renal glomeruli in all BXSB mice were analysed by immunofluorescence.Results The levels of proteinuria and the titers of serum ANA in group A and in group B mice were lower than in group C ( P 0 01,or P 0 05).The depositions of immunoglobulins in renal glomeruli were the same ( P 0 05).The levels of proteinuria in group A were lower than in group B ( P 0 05).Conclusion The results show that the mixture injection of rhuberb and radix astragali was effective to mouse SLE.
【CateGory Index】: R593.24
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Chinese Journal Full-text Database 3 Hits
1 XIA Yu-min JIANG Shan XU Shi-zheng DING Guo-hua YANG Hong-xia Depart- ment of Dermatology,Renmin Hospital of Wuhan University,Hubei 430060,China;Effect of emodin on phenotype transformation of mesangial cells induced by IgG subtype of anti-dsD-NA antibodies[J];Chinese Journal of Rheumatology;2007-05
2 PAN Xi-Gui1, WANG Yang2, LEI Xiang2, et al (1.Renmin Hospital of Wuhan University, Wuhan 430060, China;2. Pharmacy College of Wuhan University, Wuha 430072,China);Study on Extraction Procession of Astragaloside in Qihuang Oral Liquid with Orthogonal Design[J];Chinese Journal of Information on TCM;2005-03
3 DONG Yan-jun, LI Wei-dong, TU You-you, et al Departmet of Pharmacology, The school of Basic Medical Sciences, Peking University Health Science Center, Beijing (100831);Effect of Dihydro-Qinghaosu on Auto-antibody Production, TNFα Secretion and Pathologic Change of Lupus Nephritis in BXSB Mice[J];Chinese Journal of Integrated Traditional and Western Medicine;2003-09
Chinese Journal Full-text Database 10 Hits
1 Dai Chunfu (Fujian College of TCM, Fujian);Research on Prevention and Treatment Effects of Bitter-Cold Detoxicating Formula on Syndromes in the Nutrient and Blood phases of Rabbits[J];China Journal of Traditional Chinese Medicine and Pharmacy;1995-02
2 Cao Xiaofen et al (General Hospital of National Defense, Beijing);Preliminary Study of Abnormal Menstruation Suffered HysteromyomaTreated with Suogong Tong[J];China Journal of Traditional Chinese Medicine and Pharmacy;1999-04
4 Su Liwen et alDepartment of Pharmacology of Traditional Chinese Medicine ;PROPECTIVE EFFECT OF GAN LING ON RAT ACTUE HEPATIC INJURY[J];JOURNAL OF CHENGDE MEDICAL COLLEGE;1998-01
5 Zheng Chunying, Li Qingyong, Zu Yuangang(Key Laboratory of Forest Plant Ecology, Ministry of Education, Northeast Forestry University, Harbin 150040, P. R. China)/;Determination of Sugars in Glycyrrhiza uralensis by HPLC with ELSD[J];Journal of Northeast Forestry University;2006-02
6 AI Ming-xian,WU Xian-hua, LI Zuo-pin, et al. (Medical College,Hubei Institute for Nationalities,Enshi 445000,China);Protective Effects of 91WID on Leukocyte of ~(60)Co-ray Irradiated Mice[J];Journal of Hubei Institute For Nationalities Medical Edition;2004-01
7 XIN Juan,WANG Yuan-liang,GUO Li-xia,ZHU Jiu-jin(Key Laboratory for Biomechanics and Tissue Engineering Under the State Ministry of Education,College of Bioengineering, Chongqing University, Chongqing 400030,China);Recent Development of Scientific Researches on Arsenics[J];Journal of Chongqing University(Natural Science Edition);2005-01
8 Chen Min~ *1 , Li He~ 1 , Ma Wenping~ 1,2 ,Dai Yunqing~ 1 ~ 1 (College of Food Science and Nutritional Engineering, China Agricultural University,Beijing 100083) ~ 2 (Ningxia Agricultural and Forest Sciences Academy,Yinchuan 750002);Determination of Carotenoids and Carotenoid Esters Composition in Fructus Lycii by Reversed Phased High Performance Liquid Chromatography[J];Chinese Journal of Analytical Chemistry;2006-S1
9 Wang yong,Hu zhiqian,Chen zhigang,Zhang lingzhen,Wang yuanhe,Department of General Surgery,Chang Zheng Hospital,Second Miliary Medical University.Shanghai 200003;EFFECT OF ASTRAGALUS ON CELLULAR IMMUNE FUNCTION OF RATS WITH OBSTRUCTIVE JAUNDICE[J];JOURNAL OF HEPATOBILIARY SURGERY;2000-01
10 Qi Yingxin,Zhou Li,Feng Yanzhen(Guangzhou Hospital of TCM, 510370,Guangzhou,China);Chinese drugs Shuya powder for hypertension: An observation of 100 cases[J];Journal of Gansu College of Traditional Chinese Medicine;2005-04
China Proceedings of conference Full-text Database 1 Hits
1 GUO Qing Department of Senile Diseases,Taian Central Hospital,Shandong,Taian 271000,China;Efficacy observation on Shensongyangxin capsule in the treatment of insomnia[A];[C];2007
Chinese Journal Full-text Database 10 Hits
1 Wang Xinchang,Wen Chengpin,Yang Kepeng,et al Zhejiang College of TCM,Hangzhou (310053);Effect of Langchuangding on Nephritis of MRL/Ipr Lupus Mice[J];;2006-01
2 Xie Zhijun,Bian Hua Zhejiang University of TCM,Hangzhou(310053);Pro. Fan Yongsheng’s Experience in Treating Systemic Lupus Erythematosus[J];Journal of Zhejiang University of Traditional Chinese Medicine;2006-04
3 Zhang Xuan,Li Hongbin,Dong Yi,et al (Department of Rheumatology,Peking Union Medical College Hospital,Beijing 100730);High dose intravenous immunoglobulins in the treatment of systemic lupus erythematosus[J];Beijing Medical Journal;2001-02
4 Ying Kang,Wang Yuzhen (Department of Biology,Baotou Medical College,Baotou 014010,China);The Effect of Paeomy Phenol on Transformation of Lymph Cells of Mice[J];Journal of Baotou Medical College;2001-02
5 Chen Yangrong,Ren Wenying,Jiang Ming,et al ( 1 Fujian College of TCM; 2 The People’s Hospital of Fujian Province);Regulatory Action of BushenqingreFang on Apoptosis of Nephridial Tissue in Mice with Lupus Nephritis Caused by cGVHD[J];China Journal of Traditional Chinese Medicine and Pharmacy;2005-03
6 DAI Chen-xian, SUN Xiao-yun, SU Yin, LI Zhan-guo (Department of Rheumatology and Immunology, Peking University People's Hospital, Beijing 100044, China);Immunological characteristics of chronic graft versus host diseases murine model with lupus nephritis[J];Journal of Peking University(Health Sciences);2008-04
7 XU An-Ping, WANG Zhen, L Jun, LIANG Yan-Yi, YANG Pu, HUANG Hu-Hui, LAI De-YuanDepartment of Nephrology, Second Affiliated Hospital, Sun Yat-sen University, Guangzhou 510120, China;Therapeutic effects of Saikosaponin-d on lupus nephritis in NZBWF1 mice[J];Journal of the Fourth Military Medical University;2007-23
8 SHI Chenggang,YIN Peida,CHEN Yongxiong,et al.Department of Nephropathy,Third Affiliated Hospital,Sun Yat Sen University of Medical Sciences,Guangzhou 510630, China;Apoptosis in lupus nephritis patients[J];CHINESE JOURNAL OF RHEUMATOLOGY;2000-01
9 XU Chen ,WU Zhaolong,ZHANG Zhigang,GUO Muyi. Department of Nephorology,Tongji Hospital of Tongji University,Shanghai 200065,China;Effects of tripterine on local expressions of collagen type I and type IV in BW F1 mice kidney[J];Chinese Journal of Rheumatology;2002-04
10 XU Rui hong ,ZHANG Tang de,ZHAN Qing song,TAO Yi. Department of Dermatology,Navy Hospital,Guangzhou 510318,China;Effect of triptolide on the expression of CD86 on systemic lupus erythematosus B cells[J];Chinese Journal of Rheumatology;2003-05
【Secondary References】
Chinese Journal Full-text Database 7 Hits
1 WANG Jun-xia1,TANG Wei1,ZUO Jian-ping1,2(1.Laboratory of Immunopharmacology,State Key Laboratory of Drug Research,Shanghai Institute of Materia Medica,Chinese Academy of Sciences,Shanghai,201203,China;2.Laboratory of Immunology and Virology,Shanghai University of Traditional Chinese Medicine,Shanghai,201203,China);The anti-inflammatory and immunosuppressive activity of artemisinin derivatives[J];International Journal of Pharmaceutical Research;2007-05
2 Li bing,Zhang le zhi,Wang jun,Zheng jiang,Yu shuang jiang;The effect of dihydroartemisin on cytokines release from RAW 2647 cells induced by CpG ODN[J];Sichuan Journal of Physiological Sciences;2005-04
3 JIN Ou-yang,ZHANG Hua-yong,XU Ting,ZHAO Sheng-nan,ZHOU Kan-xing,SUN Ling-yun(Department of Rheumatology and Immunology,The Affiliated Drum Tower Hospital of Nanjing University Medical School,Jiangsu 210008);Pathological Change and Mechanism of Artesunate Treatment for Lupus Nephritis in MRL/lpr Mice[J];Journal of Clinical Medicine in Practice;2007-07
4 DONG Yan Jun,LI Wei Dong,TU You You 2, ZHANG Hui Na,ZOU Wan Zhong 1,YANG Lan 2,LIN Zhi Bin (The School of Basic Medical Science,Peking University Health Science Center, Dept of Pharmacology; 1Dept of Pathology,Beijing 100083 2Chinese Herb Institute,Chinese Medicine Reserch College,Beijing100700);The effects of DQHS on the pathologic changes in BXSB mice lupus nephritis and the effect mechanism[J];Chinese Pharmacological Bulletin;2003-10
5 MA Jie~1 CHEN Lihua~1 LIAO Rong~2 XU Shuguang~2 LI Min~1 XU Donghui~1 LI Weidong~(1*) (1.Department of Pharmacology, Science Health Center of Peking University , Beijing 100083, China; 2.Kunming Pharmaceutical Co., Ltd., Kunming 650106, China);Effects of artemether and dihydroarteannuin on mouse model of scleroderma[J];China Journal of Chinese Materia Medica;2009-02
6 LIN Sheng-you1,CHEN Jian1,JIN Bo2,NI Gui-bao1,FAN Yong-sheng2,WEN Cheng-ping2(1.Traditional Chinese Medicine Hospital of Zhenjiang, Hangzhou 310053,Zhejiang,China;2.Zhejiang University of TCM,Hangzhou 310006,Zhejiang,China);Influence of Early Treatment of Chinese Herbal Medicine on the Expression of TGF-β NF-κB in Kidney of Juvenile Lupus Mouse[J];Chinese Archives of Traditional Chinese Medicine;2008-06
7 LIU Wei, Wang Hui, YANG Xiao-yan, et al The First Affiliated Hospital of Tianjin College of TCM, Tianjin (300193);Clinical Observation on Treatment of Active Systemic Lupus Erythematosus with Haoqin Qingdan Decoction[J];Chinese Journal of Integrated Traditional and Western Medicine;2006-05
【Secondary Citations】
Chinese Journal Full-text Database 1 Hits
1 Gao Mei,et al. Department of Immunology, Beijing Medical University, Beijing 100083, China;The enhancing effect of Polyporus Umbellatus Polysccharide on immunological functions of mice[J];Chinese Journal of Immunology;1991-03
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