Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Chinese Journal of Rheumatology》 2003-08
Add to Favorite Get Latest Update

Association of killer cell immunoglobulin-like receptor gene polymorphisms with seronegative spondylarthropathies

GONG Wei juan,YANG Jue qin,ZHANG Lei,YAO Fang juan,FAN Li an.Shanghai Second Medical University,Shanghai Institute of Immunology,Shanghai 200025,China  
Objective To investigate whether the killer cell immunoglobulin like receptor (KIR) gene polymorphisms are associated with seronegative spondylarthropathies.Methods All 197 HLA B27 positive patients with seronegative spondyloarthro pathies (SpA) and 83 randomly ethnically matched healthy controls were enrolled to detect the KIR genotype using PCR SSP in Shanghai area.Results The KIR3DL1 gene frequency was significantly lower in the patient group (0 763) than in the control group (1 00) (RR=0 76, P =0 003).Meanwhile,the gene frequencies of two pseudogenes (KIR2DP1,KIR3DP1) were significantly higher in SpA group than in healthy control group (RR=1 1, P =0 004).Conclusion There may be a negative association between pathogenesis of SpA and KIR3DL1 gene.The function of KIR3DL1 molecule should be investigated deeply.
【Fund】: 国家自然科学基金资助项目 ( 3 9970 742 ) ;; 上海市高等学校科技基金资助项目 ( 99QB68) ;; 上海 联合利华研究与发展基金 资助项目 ( 9911)
【CateGory Index】: R684
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
【References】
Chinese Journal Full-text Database 6 Hits
1 XU Ling-di,LU Yu,ZHANG Lei,YANG Jue-qin,YAO Fang-juan,FAN Li-an,Shanghai Institute of Immunology,School of Medicine,Shanghai Jiaotong University,Shanghai 200025,China;Association of killer cell immunoglobulin like receptor (KIR) gene polymorphism with Behcet's disease[J];Chinese Journal of Rheumatology;2006-03
2 SHOU Lihong, ZHANG Huiying, PAN Yuefen, et al. Department of Hematology, Huzhou Central Hospital, Huzhou 313000, China;Expression of killer Ig like receptors 3DL1 on CD8~+ T lymphocytes in patients with idiopathic thrombocytopenic purpura[J];Clinical Education of General Practice;2009-06
3 CHEN A-Mei,GUO Xiao-Ming, YAN Wen-Ying1, XIE Song-Mei1, ZHU Na1, WANG Xin-Dang1, XU Ri1, LIU Qing-Ping2 Department of Histology and Embryology, Inner Monglia Medical College, Huhhot, 010059 China; 1Shangdong Cord Blood and Hematopoietic Stem Cell Bank, Jinan 250002, China; 2Bioengineering College, Dalian University, Dalian 116622, China;Polymorphism of Killer Cell Immunoglobulin-like Receptor Gene and Its Correlation with Leukemia[J];Journal of Experimental Hematology;2007-01
4 ZHANG Hai-qing*, ZHAO Jia-jun, ZHAO Yue-ran, LIANG Jun, SONG Huai-dong, GAO Ling. *Department of Endocrinology, Shandong Provincial Hospital, Shandong University, Jinan 250021;Association of killer cell immunoglobulin-like receptor gene polymorphisms with Graves′ disease[J];Chinese Journal of Endocrinology and Metabolism;2006-02
5 WANG Shan~*, ZHAO Yue-ran, JIAO Yu-lian, WANG Lai-cheng, XU Cheng-yan, CHEN Zi-jiang. ~*Reproductive Center of Shangdong University and Shangdong Provincial Hospital, Ji-nan 250021, China;Association of killer cell immunoglobulin-like receptors gene polymorphisms with unexplained early recurrent spontaneous abortion[J];Chinese Journal of Microbiology and Immunology;2005-12
6 HE Li-xin,CHEN A-Mei,GUO Xiao-ming,YAN Wen-ying,XU Ri,et al.(Inner Monglia Medical College,Hohhot,010059);Association of killer cell immunoglobulin-like receptor gene with chronic myelogenous leukemia[J];Chinese Journal of Birth Health & Heredity;2007-05
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 GONG Weijuan,FAN Lian,YANG Jueqin,YAO Fangjuan,XU Lingdi.Shanghai Second Medical University,Shanghai Institute of Immunology,Shanghai 200025,China;Association of MICA gene exon 2~4 polymorphism with seronegative spondylarthropathies[J];Chinese Journal of Rheumatology;2002-04
2 GONG Wei-juan,YANG Jue-qin,YAO Fang-juan,XU Ling-di,FAN Li-an.Shanghai Institute of Immunology,Shanghai Second Medical University,Shanghai 200025,ChinaCorresponding author: FAN Li-an,Email: Lianfan1@hotmail.com,Tel:021-63846590-776541;Influences of three different HLA-B antigens expression on K562 cells on cytotoxicity of peripheral natural killer cells from seronegative spondyloarthropathies patients[J];Chinese Journal of Rheumatology;2004-04
3 Cai Qing,Liu Cheng-gang,Zhan Zhi,Chen Tao,Zhu Mei-cai(General Hospital of Air Force,PLA,Beijing 100036,China);Gene Polymorphism of Tumor Necrosis Factor α-857 and-863 Sites in Ankylosing Spondylitis[J];Clinical Journal of Medical Officers;2009-02
4 HE Ying-zhi, GUO Kun-yuan, MEI Jia-zhuan, NIU Xin-qing, ZHOU Jian (Department of Hematology, Zhujiang Hospital, Southern Medical University, Guangzhou 510582, China);Disparity in cytotoxicity of allo-NK cells against ECV304 cells and potential mechanisms[J];Immunological Journal;2007-06
5 JIAO Yu-lian~(1,2),MA Chun-yan~1,CUI Bin~1,WANG Lai-cheng~1,ZHANG Jie~1,LIU Yi-qing~1,ZHANG Xue~1,CHEN Zi-jiang~1,ZHAO Yue-ran~(1,2)(1.Medical Research Centre,Shandong Provincial Hospital,Shandong University,Jinan 250021,Shandong,China;2.Institute of Basic Medicine,Shandong Academy of Medical Sciences,Jinan 250062,Shandong,China);Association between polymorphisms of killer cell immunogloblin-like receptor gene and ankylosing spondylitis[J];Journal of Shandong University(Health Sciences);2006-11
6 MENG Qing-guo1,LU Yong-tian1,2,FAN Xian-liang3 (1.School of Medicine,Shandong University,Jinan 250012,China;2.Department of Otolaryngology,Shenzhen Second People's Hospital,Shenzhen 518035,Guangdong,China;3.Department of Otolaryngology & Head and Neck Surgery,Second Hospital of Shandong University,Jinan 250033,China);Association of killer cell immunoglobulin-like receptor gene polymorphisms with nasopharyngeal carcinoma[J];Journal of Otolaryngology and Ophthalmology of Shandong University;2008-03
7 GONG Wei juan,YANG Jue qin,YAO Fang juan,XU Ling di,FAN Li an(Shanghai Instituite of Immunology,Shanghai Second Medical University,Shanghai 200025,China);Expression of HLA-B Antigen on K562 Cell and Analysis of Its Influence on Cytotoxicity Mediated by NK from PBMC[J];;2003-04
8 ZHANG Cai-e, HAN Jun-yan, YANG Hui-jun, WU Xiong-wen~(*), HUANG Ya-fei, LIANG Zhi-hui, GONG Fei-liDepartment of Immunology, Tongji Medical College, Huazhong (University) of Science and Technology, Wuhan 430030, China;HLA-G1 molecule expressed by ECV304 cells inhibit cytotoxic activity of allogeneic NK cells[J];Journal of Cellular and Molecular Immunology;2005-06
9 SU Hong~1,WANG Bao-long~2,ZHANG Xiu-jun~1,HAO Jia-hu~1,XIAO Qin~1,YE Dong-qing~1. ~1(Department of Epidemiology and Statistics,Anhui Medical University,Hefei,Anhui,230032 P.R. China); ~2(Department of Transfusion in Anhui Provincial Hospital,Hefei,Anhui,230001 P.R. China);Disequilibrium linkage between the polymorphism in exons 2,3 and 4 of the MICA gene and HLA-B antigen of patient with ankylosing spondylitis[J];Chinese Journal of Medical Genetics;2006-04
10 GONG Wei-Juan,YANG Yu-Qin,YAO Fang-Juan,XU Ling-Di,FAN Li-An.Shanghai Second Medical University,Shanghai Institute of Immunology,Shanghai 200025,China;Influences of two different HLA-B antigens on receptors expression of NK cells from peripheral blood lymphocytes[J];Chinese Journal of Immunology;2004-10
【Co-references】
Chinese Journal Full-text Database 10 Hits
1 FU Shao-Jie1, YU Li-Xin1, LUO Min2, XIAO Lu-Lu2, WANG Yi-Bin1, XU Jian1, DU Chuan-Fu1, DENG Wen-Feng11Department of Organ Transplantation,2Tissue Typing Center, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China;Association between inhibitory KIR genotype assortment and acute rejection after kidney transplantation[J];Journal of the Fourth Military Medical University;2009-10
2 XIAO Lu-lu, HAO Gui-qin, YE Xin, CHEN Hong-tao, TAN Yin, ZHANG Sheng Guangzhou Tissue Typing Centre, Guangzhou 510095, China;HLA genotyping by automatic semi-quantitative polymerase chain reaction-reverse sequence specific oligonucleotide[J];Journal of First Military Medical University;2003-01
3 XIE Shangkui ,FENG Shufang,SHEN Fumin. Department of Dermatology Huashan Hospital,Shanghai Medical University,Shanghai 200040,China;Relationship between HLA class Ⅱ genes and organ,system involvement in patients with systemic lupus erythematosus.[J];CHINESE JOURNAL OF RHEUMATOLOGY;2000-04
4 XU Ling-di,LU Yu,ZHANG Lei,YANG Jue-qin,YAO Fang-juan,FAN Li-an,Shanghai Institute of Immunology,School of Medicine,Shanghai Jiaotong University,Shanghai 200025,China;Association of killer cell immunoglobulin like receptor (KIR) gene polymorphism with Behcet's disease[J];Chinese Journal of Rheumatology;2006-03
5 LAN Yuxiao,DENG Zhihui.Shenzhen Blood Center,Shenzhen 518035,China;Study on the genotyping of HLA-Cw locus by sequence based typing method[J];Jiangxi Journal of Medical Laboratory Sciences;2006-04
6 Zhang Jian (The International Peace Maternity and Child Health Hospital of the China Welfare Institute, Shanghai 200030);Etiological Study of Early Recurrent Spontaneous Abortion[J];Clinical Medical Journal of China;2003-04
7 YIN Xiao-lin(Department of Haematology, Zhujiang Hospital, First Military Medical University, Guangzhou 510282, China);Evolution,expression,and function of killer immunoglobulin-like receptor gene[J];Immunological Journal;2004-S1
8 JIAO Yu-lian~(1,2),MA Chun-yan~1,CUI Bin~1,WANG Lai-cheng~1,ZHANG Jie~1,LIU Yi-qing~1,ZHANG Xue~1,CHEN Zi-jiang~1,ZHAO Yue-ran~(1,2)(1.Medical Research Centre,Shandong Provincial Hospital,Shandong University,Jinan 250021,Shandong,China;2.Institute of Basic Medicine,Shandong Academy of Medical Sciences,Jinan 250062,Shandong,China);Association between polymorphisms of killer cell immunogloblin-like receptor gene and ankylosing spondylitis[J];Journal of Shandong University(Health Sciences);2006-11
9 ZHANG Lei 1, Katharine C Hsu 2, LIU Xiao rong 2, YANG Jue qin 1, YAO Fang juan 1, XU Ling di 1, Bo Dupont 2, FAN Li an 1(1 Shanghai Institute of Immunology, Shanghai Second Medical University, Shanghai 200025,China; 2 Memorial Sloan Kettering Cancer Center, New York, USA);A Study on Human KIR Genotyping by PCR-SSP and Haplotype Defined by the Analysis of Family Segregation[J];Shanghai J.of Immunology;2003-02
10 ZHANG Lei,FAN Li-an,YANG Jue-qin,YAO Fang-juan,XU Ling-di(Shanghai Institute of Immunology,Shanghai Second Medical University,Shanghai 200025,China);Diversity of KIR2DL5 Gene Subtype Content and Haplotype Analysis in Chinese Han Population in Shanghai Arca[J];;2004-03
【Secondary References】
Chinese Journal Full-text Database 9 Hits
1 Cheng-Yan XU,Shan WANG,Yu-Hua SHI,Zi-Jiang CHEN,Yu-Lian JIAO,Yue-Ran ZHAO (Center for Reproductive Medicine,Shandong Provincial Hospital,Shandong University,Jinan,250021);Analysis of HLA-Cw Alleles in Couples with Recurrent Spontaneous Abortion[J];Reproduction & Contraception;2008-05
2 ZHANG Hai-qing1,ZHAO Jia-jun1,ZHAO Yue-ran2,GAO Ling2,GUAN Qing-bo1,Liao Lin1,JIAO Yu-lian2 (1.Department of Endocrinology;2.Central Laboratory,Shandong Provincial Hospital Affiliated to Shandong University,Jinan 250021,China);Genotypes of killer cell immunoglobulin-like receptors in Hashimoto′s thyroiditis patients[J];Journal of Shandong University(Health Sciences);2009-08
3 SHOU Lihong, ZHANG Huiying, PAN Yuefen, et al. Department of Hematology, Huzhou Central Hospital, Huzhou 313000, China;Expression of killer Ig like receptors 3DL1 on CD8~+ T lymphocytes in patients with idiopathic thrombocytopenic purpura[J];Clinical Education of General Practice;2009-06
4 CHEN A-mei1,2,LIU Qing-ping1,CUI Xiao-ying2,CUI Ming-yu2,YAN Wen-ying3,XIE Song-mei3,ZHU Na3,WANG Xin-dang3 1Bioengineering College,Dalian University,Dalian 116622;2Department of Histology and Embryology Inner Mongolia Medical College,Huhohote 010059;3Shandong Umbilical Cord Blood Hematopoietic Stem Cell Bank,Jinan 250002,China;Study on the polymorphism of killer cell immunoglobulin like receptor (KIR) gene with systemic lupus erythematosus of North population in China[J];Chinese Journal of Cellular and Molecular Immunology;2008-08
5 LIU wen-zhong,YUN Yu-guang,CHEN A-Mei.(Inner Monglia Medical College Huherhaoter,010059);Study the polymorphisms of HLA-A,alleles in patients with chronic myelogenous leukemia in inner mongolia[J];Chinese Journal of Birth Health & Heredity;2009-04
6 SHI Yan1,LI Li1,2,FAN Weimin1,SUN Hao1,HE Chengtao1,CUI Yan1(1.Department of Laboratory Medicine,Clinical Medical College,Southeast University,Jiangsu,Nanjing 210009,China;2.Department of Immunology Laboratory,Zhong Da Hospital,Southeast University,Jiangsu,Nanjing 210009,China);The polymorphism of killer cell immunoglobulin-like receptors genotype in patients with Siogren's syndrome[J];Journal of Molecular Diagnostics and Therapy;2009-04
7 SUN Hao1, LI Li1,2, FAN Weimin1, SHI Yan1, HE Chengtao1, CUI Yan1(1.Department of Laboratory Medicine, Clinical Medical College, Southeast University, Jiangsu, Nanjing 210009, China;2.Department of Immunology Laboratory, Zhong Da Hospital, Southeast University, Jiangsu, Nanjing 210009, China);Investigation of the killer cell immunoglobulin-like receptors gene polymorphisms of patients with rheumatoid arthritis[J];Journal of Molecular Diagnostics and Therapy;2010-01
8 XU Jin-E,YANG Xiao-Ju,ZHANG Yun,JIANG Xiu-Li,CHEN Zi-Jiang.Department of Reproductive Medicine,the Affiliated Hospital to Qingdao University Medical College,Qingdao 266003,China;Association of killer-immunoglobulin-like receptors/human leukocyte antigen(HLA)-C and early recurrent spontaneous abortion[J];Chinese Journal of Immunology;2010-05
9 XU Jin'e,ZHANG Yun,WANG Shan,SHI Yu-hua,CHEN Zi-jiang. The Affiliated Hospital to QingDao University Medical College,QingDao 266003,China;Association of human leukocyte antigen (HLA)-C molecules on trophoblast cells and unexplained recurrent spontaneous abortion[J];Chinese Journal of Practical Gynecology and Obstetrics;2010-08
China Proceedings of conference Full-text Database 1 Hits
1 Yun yu-guang Na qin Cui ming-yu,Chen a-mei;Study the polymorphisms of HLA-A、B alleles in patient with leukemia in Inner Mongolin[A];[C];2010
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved