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《Chinese Journal of Rheumatology》 2006-03
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Association of killer cell immunoglobulin like receptor (KIR) gene polymorphism with Behcet's disease

XU Ling-di,LU Yu,ZHANG Lei,YANG Jue-qin,YAO Fang-juan,FAN Li-an,Shanghai Institute of Immunology,School of Medicine,Shanghai Jiaotong University,Shanghai 200025,China  
Objective To investigate whether the killer cell immunoglobulin-like receptor (KIR) gene polymorphism is associated with Behcet's disease (BD). Methods Ninety-five patients with BD in nationality Han in Shanghai area and 87 randomly ethnically matched controls were enrolled to detect the KIR genotype using PCR-SSP. Results The KIR3DL1 gene frequency was significantly lower in patients with BD (0.728) than in the healthy controls (1.00) (RR=0.067, P=0.009). The rest of the gene frequency was found to have no statistically significant difference compared with the healthy controls. Conclusion There may be a negative association between the pathogenesis of BD and KIR3DL1 gene. The function of KIR3DL1 molecule should be investigated further.
【Fund】: 上海市高等学校科技基金资助项目(02BZ31);; 上海交通大学医学院自然科学研究基金资助项目(02XJ21012)
【CateGory Index】: R597
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【References】
Chinese Journal Full-text Database 1 Hits
1 SHOU Lihong, ZHANG Huiying, PAN Yuefen, et al. Department of Hematology, Huzhou Central Hospital, Huzhou 313000, China;Expression of killer Ig like receptors 3DL1 on CD8~+ T lymphocytes in patients with idiopathic thrombocytopenic purpura[J];Clinical Education of General Practice;2009-06
【Citations】
Chinese Journal Full-text Database 3 Hits
1 GONG Wei juan,YANG Jue qin,ZHANG Lei,YAO Fang juan,FAN Li an.Shanghai Second Medical University,Shanghai Institute of Immunology,Shanghai 200025,China;Association of killer cell immunoglobulin-like receptor gene polymorphisms with seronegative spondylarthropathies[J];Chinese Journal of Rheumatology;2003-08
2 ZHANG Lei 1, Katharine C Hsu 2, LIU Xiao rong 2, YANG Jue qin 1, YAO Fang juan 1, XU Ling di 1, Bo Dupont 2, FAN Li an 1(1 Shanghai Institute of Immunology, Shanghai Second Medical University, Shanghai 200025,China; 2 Memorial Sloan Kettering Cancer Center, New York, USA);A Study on Human KIR Genotyping by PCR-SSP and Haplotype Defined by the Analysis of Family Segregation[J];Shanghai J.of Immunology;2003-02
3 XU Ling-di, LU Yu, FAN Li-an, YANG Jue qin, YAO Fang-Juan , GU Yue-ying(Shanghai Institute of Immunology, Shanghai Second Medical University, Shanghai 200025, China; Department of Rheumatology, Renji Hospital, Shanghai Second Medical University, Shanghai 200001, China);Study on the association between the HLA-B*51 gene with Behcet's disease in Shanghai area[J];;2005-02
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 HE Cheng-tao1,LI Li1,2,ZHANG Jian-qiong3,et al.(1.Department of Laboratory Medicine,Clinical Medical College of Southeast University,Nanjing 210009;2.Department of Immunology Laboratory,Zhongda Hospital,Southeast University,Nanjing 210009;3.Key Laboratory of Developmental Genes and Human Diseases,Ministry of Education,Nanjing 210009,Jiangsu,China);Polymorphism of killer-cell immunoglobulin-like receptor gene family in Han blood donors in Jiangsu[J];Chinese Journal of Clinical Laboratory Science;2009-03
2 SHOU Lihong, ZHANG Huiying, PAN Yuefen, et al. Department of Hematology, Huzhou Central Hospital, Huzhou 313000, China;Expression of killer Ig like receptors 3DL1 on CD8~+ T lymphocytes in patients with idiopathic thrombocytopenic purpura[J];Clinical Education of General Practice;2009-06
3 ZHANG Lei,FAN Li-an,YANG Jue-qin,YAO Fang-juan,XU Ling-di(Shanghai Institute of Immunology,Shanghai Second Medical University,Shanghai 200025,China);Diversity of KIR2DL5 Gene Subtype Content and Haplotype Analysis in Chinese Han Population in Shanghai Arca[J];;2004-03
4 REN Shao-min,YANG Guang-lu,LIU Chun-zhi,ZHANG Chun-xia,YU Shao-fei,LI Wei-cai(Department of Pediatrics,the First Affiliated Hospital of Inner Mongolia Medical College,Huhehot 010050,China);Investigation and sequencing analysis on the HLA-A and B-relevant genes in Henoch-purpura of children of Mongolian and Han populations in internal Mongolia region[J];Current Immunology;2009-01
5 XU Jin-huan,ZHANG Jian-qiong,PAN Ning,JIANG Wei,MIAO Feng-qin,XIE Wei(Basic Medical Science School,Southeast University,Nanjing 210009,China);Polymorphism of the immunoglobulin-like receptors gene in killer cells of Chinese Han population[J];Current Immunology;2009-04
6 CHEN A-mei1,2,LIU Qing-ping1,CUI Xiao-ying2,CUI Ming-yu2,YAN Wen-ying3,XIE Song-mei3,ZHU Na3,WANG Xin-dang3 1Bioengineering College,Dalian University,Dalian 116622;2Department of Histology and Embryology Inner Mongolia Medical College,Huhohote 010059;3Shandong Umbilical Cord Blood Hematopoietic Stem Cell Bank,Jinan 250002,China;Study on the polymorphism of killer cell immunoglobulin like receptor (KIR) gene with systemic lupus erythematosus of North population in China[J];Chinese Journal of Cellular and Molecular Immunology;2008-08
7 ZHANG Hai-qing,ZHAO Jia-jun,ZHAO Yue-ran,GUAN Qing-bo,GAO Ling,SONG Huai-dong Department of Endocrinology,Shandong Provincial Hospital Affiliated to Shandong University,Jinan 250021,China[;Genotype analysis of killer cell immunoglobulin-like receptors in Graves' disease patients[J];Chinese Journal of Cellular and Molecular Immunology;2009-08
8 Hong Yan,Lin Qide,Wang Xipeng.Department of Obstetrics and Gynecology,Renji Hospital,Shanghai Second Medical University,Shanghai 200001;The relationship between the expression of KIR′ repertoire in decidua and unexplained spontaneous abortion.[J];Progress In Obstetrics and Gynecology;2005-03
9 CHEN A-Mei,GUO Xiao-Ming, YAN Wen-Ying1, XIE Song-Mei1, ZHU Na1, WANG Xin-Dang1, XU Ri1, LIU Qing-Ping2 Department of Histology and Embryology, Inner Monglia Medical College, Huhhot, 010059 China; 1Shangdong Cord Blood and Hematopoietic Stem Cell Bank, Jinan 250002, China; 2Bioengineering College, Dalian University, Dalian 116622, China;Polymorphism of Killer Cell Immunoglobulin-like Receptor Gene and Its Correlation with Leukemia[J];Journal of Experimental Hematology;2007-01
10 DAI Yu-Dong,DONG Rui-Ping,DU Hai-LinDepartment of Research,Nanjing Red Cross Blood Center,Nanjing 210003,Jiangsu Province, China;Polymorphism of Human Killer Cell Immunoglobulin-like Receptor Gene in Chinese Jiangsu Han Population[J];Journal of Experimental Hematology;2010-03
【Co-references】
Chinese Journal Full-text Database 10 Hits
1 GONG Wei juan,YANG Jue qin,ZHANG Lei,YAO Fang juan,FAN Li an.Shanghai Second Medical University,Shanghai Institute of Immunology,Shanghai 200025,China;Association of killer cell immunoglobulin-like receptor gene polymorphisms with seronegative spondylarthropathies[J];Chinese Journal of Rheumatology;2003-08
2 BIAN Xiao-xia,YANG You-lin(Department of Gastroenterology,The First Clinical Medical College of Harbin Medical University,Harbin 150001,China);The Relationship Between Genotype Polymorphism of Interferon-γ and Ulcerative Colitis[J];Heilongjiang Medical Journal;2008-02
3 LU Bei-yan,HU Yu-hong,LI Wei (The First Affiliated Hospital, Jiamusi University,Jiamusi 154003,China);Alternation in biologic characteristics of natural killer cells in pregnancy induced hypertension[J];Heilongjiang Medicine and Pharmacy;2005-04
4 Zhang Jian (The International Peace Maternity and Child Health Hospital of the China Welfare Institute, Shanghai 200030);Etiological Study of Early Recurrent Spontaneous Abortion[J];Clinical Medical Journal of China;2003-04
5 VAN Wei-hua (Shanghai Institute of Immunology, Shanghai Second Medical University, Shanghai 200025, China);Structure and function of NK cell receptor KIR2DL4[J];Immunological Journal;2003-S1
6 YIN Xiao-lin(Department of Haematology, Zhujiang Hospital, First Military Medical University, Guangzhou 510282, China);Evolution,expression,and function of killer immunoglobulin-like receptor gene[J];Immunological Journal;2004-S1
7 CHI Yong-bin, ZHANG Lei, YANG Jue-qin, YAO Fang-juan, XU Ling-di, Fan Li-an (Shanghai Institute of Immunology, Shanghai Second Medical University, Shanghai 200025, China);The diversity of KIR gene content and haplotype analysis in Xinjiang Uygur and Yunnan Yi populations in China[J];;2005-03
8 ZHOU Guang-Jin, YU Long, ZHAO Shou-Yuan(Institute of Genetics, Fudan University, Shanghai 200433, China);The pseudogenes of human genome[J];Chinese Bulletin of Life Sciences;2004-04
9 Hong Yan,Lin Qide,Wang Xipeng.Department of Obstetrics and Gynecology,Renji Hospital,Shanghai Second Medical University,Shanghai 200001;The relationship between the expression of KIR′ repertoire in decidua and unexplained spontaneous abortion.[J];Progress In Obstetrics and Gynecology;2005-03
10 Min-Qiang Shen, Zhan-Ju Liu, Department of Gastroen-terology, the Second Affiliated Hospital of Zhengzhou Uni-versity, Zhengzhou 450014, Henan Province, ChinaMin-Qiang Shen, Department of Gastroenterologey, the 152th Hospital of Chinese PLA, Pingdingshan 467000, Henan Province, China;NK cell activation and immune response in inflammatory bowel disease[J];World Chinese Journal of Digestology;2008-28
【Secondary Citations】
Chinese Journal Full-text Database 2 Hits
1 Huang Cibo, Liu Yi, Cai Xinghua Xu Ming, Ding Yuzhen, Meng Qingong (Department of Rheumatology, General Hospial of PLA, Beijing 100853);Determination of HLA antigen in Behcet's disease[J];ACADEMIC JOURNAL OF PLA POSTGRADUATE MEDICAL SCHOOL;1997-01
2 Tian Ding; Mineshita S; Wang Liman; et al. (Xuanwu Hospital, CUMS Beijing 100053);HLA-B51 ASSOCIATED WITH BEHCET'S DISEASE IN NORTHERN HAN CHINESE[J];CHINESE JOURNAL OF MEDICAL CENETICS;1994-05
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