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《Radialization Protection》 2003-02
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THE GENOMIC INSTABILITY INDUCEDBY ~(60)Co γ RAY RADIATION

Chen Rui Wang Zhongwen Cao Yi Wang Xiaoli Xing Xiaohong(China Institute for Radiation Protection, Taiyuan, 030006)  
In this paper, the China hamster lung fibroblasts (CHL) cell′s genomic instability induced by 60 Co γ rays was studied by the methods of single cell gel electrophoresis (SCGE) and cloning efficiency. The fast growing cells were grouped and then irradiated by 60 Co γ rays. After 33 population doubling, the progenies were secondly irradiated with 2 Gy 60 Co γ rays. The results showed that the second damage was correlated with the original irradiation dose. It can be concluded that the 60 Co γ rays can not only induce the immediate biological effects in CHL cells, but also can lead to the genomic instability in the descendants.(
【CateGory Index】: Q64
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