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PROTECTIVE EFFECT OF POLYSACCHARIDES OF HUANGMO ON MICE EXPOSED TO X RAYS

Ye Fei Su Shijie Cao Ruimin(School of Preventive Medicine, Norman Bethune University of Medical Sciences, Changchun, 130021)  
The protective effect of polysaccharides of Huangmo (a kind of mushroom) (PSH) given preventively to mice exposed to X rays on their 30 day survival rate and immunologic function was observed. The results show that PSH increased the 30 day survival rate in mice exposed to a lethal dose of X rays, with the protection index being up to 1.72, which suggest that the protective effect of PSH is similar to that of polysaccharides of Ginseng. In addition, in mice exposed to a dose of 2.0 Gy, PSH significantly enhanced the ability of splenocytes to produced IL 2 and γ IFN, activated splenic NK cells, and speeded up the progression of cell cycle in thymocytes, which suggest that for PSH, there may be a certain protective effect on mice exposed to X rays, with enhancing their immunologic function significantly.
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