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《Journal of Nurses Training》 2014-11
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Clinical observation of acupoint autohemo-therapy combined external application of acne powder for the treatment of acne and effects on tumor necrosis factor-a,interleukin 8

Zhao Yuefeng;Shenzhen Prefecture Traditional Chinese Medicine Hospital;  
Objective To study the mechanism of autoblood point injection therapy combined with acne powder for the treatment of tumor necrosis factor alpha(TNF-α)and effect on serum interleukin 8(IL-8).Method 180patients with facial acne from 2012November to 2013October admitted to Department of Dermatology were selected and randomly divided into observation group,control group 1and control group 2.60cases in each group.Observation group were treated with acupuncture Autohemotherapy and external application of acne powder for facial acne treatment.Patients in control group 1was given acupoint Autohemotherapy.Patients in control group 2was given orally 2roxithromycin capsules and topical adapalene gel.Another 50cases of healthy people without making any treatment was selected as control group 3.The therapeutic effect of acne,patients with lesions,and lesions counts of TNF-αand IL-8index.was measured before treatment,after fourth weeks,eighth weeks,Twelfth weeks in three groups.Result In the observation group,the cure rate and total effective rate was better than that of control group,There was significant difference(P0.05).The average number of lesions in observation group was decreased before treatment,after fourth weeks,eighth weeks,Twelfth weeks compared with control group.There was significant difference(P0.05).The TNF- αand IL-8in observation group before treatment,after fourth weeks,eighth weeks,,twelfth weeks was significant difference compared with control group(P0.05).Conclusion Using autoblood point injection therapy combined with acne powder for the treatment of facial acne and the implementation of professional nursing,can effectively promote the recovery of acne,and the total effective rate.TNF-α and IL-8are involved in the pathogenesis of acne,proportional to the severity of acne,plays an important role in the formation of acne lesions,in addition,along with the time growth,TNF-αand IL-8decreased significantly,which indicated that the combined therapy has obvious curative effect on.
【Fund】: 2012年广东省深圳市科技计划项目(医疗卫生类)编号:201203154
【CateGory Index】: R248
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