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《Journal of Nurses Training》 2014-11
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Clinical observation of acupoint autohemo-therapy combined external application of acne powder for the treatment of acne and effects on tumor necrosis factor-a,interleukin 8

Zhao Yuefeng;Shenzhen Prefecture Traditional Chinese Medicine Hospital;  
Objective To study the mechanism of autoblood point injection therapy combined with acne powder for the treatment of tumor necrosis factor alpha(TNF-α)and effect on serum interleukin 8(IL-8).Method 180patients with facial acne from 2012November to 2013October admitted to Department of Dermatology were selected and randomly divided into observation group,control group 1and control group 2.60cases in each group.Observation group were treated with acupuncture Autohemotherapy and external application of acne powder for facial acne treatment.Patients in control group 1was given acupoint Autohemotherapy.Patients in control group 2was given orally 2roxithromycin capsules and topical adapalene gel.Another 50cases of healthy people without making any treatment was selected as control group 3.The therapeutic effect of acne,patients with lesions,and lesions counts of TNF-αand IL-8index.was measured before treatment,after fourth weeks,eighth weeks,Twelfth weeks in three groups.Result In the observation group,the cure rate and total effective rate was better than that of control group,There was significant difference(P0.05).The average number of lesions in observation group was decreased before treatment,after fourth weeks,eighth weeks,Twelfth weeks compared with control group.There was significant difference(P0.05).The TNF- αand IL-8in observation group before treatment,after fourth weeks,eighth weeks,,twelfth weeks was significant difference compared with control group(P0.05).Conclusion Using autoblood point injection therapy combined with acne powder for the treatment of facial acne and the implementation of professional nursing,can effectively promote the recovery of acne,and the total effective rate.TNF-α and IL-8are involved in the pathogenesis of acne,proportional to the severity of acne,plays an important role in the formation of acne lesions,in addition,along with the time growth,TNF-αand IL-8decreased significantly,which indicated that the combined therapy has obvious curative effect on.
【Fund】: 2012年广东省深圳市科技计划项目(医疗卫生类)编号:201203154
【CateGory Index】: R248
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【Co-citations】
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1 Li Jian;Zhang Yanqin;Wu Fei;Department of Dermatology,the Second People's Hospital of Wuhu;;A clinical characteristics analysis of 581 chronic urticaria patients with positive skin prick test[J];Anhui Medical Journal;2014-03
2 MU Xinhua;HE Yong;DENG Liehua;Department of Dermatology,First Affiliated Hospital of Jinan University;;Observation of recent clinical efficacy of loratadine combined with compound flumethasone ointment in treatment of chronic eczema[J];China Medicine and Pharmacy;2014-05
3 FANG Zhixiang;HE Yong;DENG Liehua;Department of Dermatology, First Affiliated Hospital of Jinan University;;Clinical short-term efficacy observation of mometasone furoate cream combined with compound glycyrrhizin tablets in treatment of chronic eczema[J];China Medicine and Pharmacy;2014-06
4 MAO Taisheng;MAO Ning;WU Tingting;HAN Jinzhi;Department of Dermatology and STD,Taihe People's Hospital;;Clinical observation of compound glycyrrhizin capsules in treatment 318 patients with skin disease[J];China Medicine and Pharmacy;2014-09
5 Liang Lijun;Liang Dan;Pharmaceutical Department,Sun yat-sen memorial hospital of sun yat-sen university;;Clinical analysis of Pregabalin in the treatment of 43 cases of Postherpetic Neuralgia[J];Journal of North Pharmacy;2014-08
6 GAO Zi-ping;LIU Wang;Teaching Hospital of Chengdu University of Traditional Chinese Medicine;Zigong First People's Hospital;;Clinical efficacy observation of the disease involving Weifen and Yingfen differentiation symptoms in the treatment of the psoriasis vulgaris in active stage[J];China Journal of Traditional Chinese Medicine and Pharmacy;2014-10
7 Xu Li;Dermatology Department of Pingchuan People's Hospital;;Clinical observation on flat warts of 80 cases treated with Huayuruanjianpingyou Decoction[J];Journal of Gansu College of Traditional Chinese Medicine;2014-04
8 LI Lin;TANG Yuying;Chengguan Hospital of SuZhou District;Jiuquan Municipality ,TCM Hospital;;XiFeng ZhiYang Tang in Treating 50 Senile Patients with Cutaneous Pruritus[J];Western Journal of Traditional Chinese Medicine;2014-08
9 MA Zhen-you;ZHANG Guang-zhong;Institute of Dermatology of Ma Zhenyou;Department of Dermatology,Beijing Chinese Medicine Hospital Affiliated to Capital Medical University;;Discussion on the definition of external preparation for cosmetic dermatology[J];Chinese Journal of Aesthetic Medicine;2014-01
10 JIN Li-hua;HU De-xin;LOU Hang-fang;Department of Obstetrics and Gynecology,The Second Hospital Affiliated to Zhejiang Chinese Medical University;Department of Orthopedics,Hangzhou Red Cross Hospital;College of Basic Medine,Zhejiang Chinese Medical University;;The clinical effects of Bupleurum injection on female genital condyloma and the load of HPV-DNA on the lesions[J];Health Research;2014-02
【Secondary Citations】
Chinese Journal Full-text Database 1 Hits
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