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《Journal of Radioimmunology》 2007-05
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Clinical Significance of Changes of Serum SCC-Ag,CA19-9 and CEA Levels in Patients with Lung Cancer

Li Bin,Zhou Haizhong,Cao Jianxia Department of Nuclear Medicine,SuBei People's Hospital of Jiangsu Province(225001)  
Objective To investigate the clinical significance of changes of serum squamous cell carcinoma antigen(SCC-Ag) and cancer antigen19-9(CA19-9) and carcinoembryanic antigen(CEA) levels in patients with lung cancer.Methods The serum levels of SCC-Ag(with MEIA),CA19-9 and CEA(with CLIA) levels determined in 98 patients with lung cancer,50 patients with benign lung diseases and(35 on 25 controls).Results The serum levels of SCC-Ag,CA19-9 and CEA in the patients with lung cancer were significantly higher than those in patients with benign lung disease and controls(P0.01).Among the cancer patients,the serum SCC-Ag levels in patients with squamous cell carcinoma were significantly higher than those in patients with adenocarcinoma,the reverse was true for serum CA19-9 and CEA levels.As the disease progressed from stageⅠ to stageⅣ,the levels of these markers also progreesively increased.Conclusion The combined determinotion of three tumor markers could be helpful for the diagnosis,prediction of prognosis and monitoing recurrence in patients with lung cancer.
【CateGory Index】: R734.2
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