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《Radiologic Practice》 2003-01
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Percutaneous microwave coagulation therapy for malignant hepatic tumor:preliminary study

WANG Jingbing,FENG Gansheng,LIANG Huimin,et al.Department of Interventional Radiology,Xiehe hospital,Tongji Medical college,Huazhong Science and Technology University,Wuhan 430022  
Objective:To evaluate the short term curative effect of percutaneous microwave coagulation therapy (PMCT) for malignant hepatic tumor and to investigate the indications and the associated factors with the treatment.Methods:44 patients of 52 hepatic tumors measured from 2.3cm to 8.6cm in the largest diameter,underwent 116 times of PMCT with 323 points guided by ultrasonography or CT.Each point was done with microwave export power 40~60 watts and working times 3~6 minutes.Then observed was the change of the following as the size and necrosis of the tumor,the level of serum AFP/CEA,liver function and associated complications.Results:After treatment,enhanced CT or MRI de ̄monstrated non enhancement of tumor lesions in 69.2%(36/52),of them 34 were less than 5 cm in diameter;obvious reduction of tumor size in 35 tumors(67.3%).The level of AFP in 28(28/32)cases with primary hepatic cancer (PHC)and CEA in 8 with metastasis decreased significantly,and the level of AFP decreased to normal in 8 cases with PHC.All the patients following the procedure had mild injure of liver function.3 patients had self limited hemorrhage in abdominal cavity.A little responsive pleural effusion in 5 and ascites in 6 were healed by conservative treatment.Conclusion:PMCT is safe and effective for the treatment of hepatic malignancy.The tumor of less than 5cm in diameter can mostly be ablated in situ and the tumor size of greater than 5 cm in diameter receiving repeated treatment can significantly be reduced.
【CateGory Index】: R735.7
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