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《Radiologic Practice》 2003-04
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Preliminary application of perfusion imaging in neoplasms in the brain and body with multislice helical CT

LI Zhiyong,WU Jianlin,NING Dianxiu,et al.Department of Radiology,the First Affiliated Hospital,Dalian Medical University,Liaoning 116011  
Objective:To evaluate methods of perfusion imaging in neoplasms with multi slice helical CT and its clinical application value.Methods:Ten patients with newly diagnosed neoplasms underwent perfusion imaging with mutislice helical CT (MSCT).At first plain CT scan was performed to localize central slices of tumor,then perfusion imaging of neoplasms was undergone using cine scan (1 rotate/s),slice thick 10mm/2i,injecting dosage 45~50ml,injecting rate 3.5~ 4.0ml/s, scanning delay time 5s,scanning total time 45s.Scanning images were transferred into ADW3.1 work station to create and analyze perfusion images and parameters,including blood flow(BF)?blood volume(BV)?mean transit time(MTT) and permeability surface (PS).Results:Perfusion images of all neoplasms can clearly and directly display tumor diameter and outlines and quantitatively monitor blood perfusion status of tumor inner structures,clearly differentiate edema and tumor in cerebral neoplasms.Perfusion parameters of all neoplasms showed remarkable increase.Body tumors were liable to be interfered by breath movement.Conclusion:MSCT perfusion imaging provides a precise and relative simple method to quantitatively estimate blood perfusion status in tumor of the body.The technique can be easily implemented and it opens up broad prospects for clinical application.
【CateGory Index】: R730.4
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