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Imaging diagnosis of non-Hodgkin′s lymphoma of bone

PENG Jia-you,ZHANG Jia-xiong,SHI De-gang,et al.Department of Radiologic,Foshan Hospital of Tradition Chinese Medicine,Guangdong 528000,P.R.China  
Objective:To discuss X-ray,CT and MR findings of non-Hodgkin lymphoma of bone.Methods:The X-ray,CT and MRI findings of 20 patients with non-Hodgkin lymphoma of bone proved pathologically were retrospectively analysed. Results:13 cases were primary NHL of bone and 7 cases were secondary NHL.There was B-cell origin in 18 cases and T-cell origin in 1 case and histocyte in 1 case.The lesions involved single bone in 14 and multiple bone in 6 (pelvis 10,femur 6 and fertibrae 6).X-ray and CT findings:lesions were osteolytic in 6 cases,infiltrative in 4 cases,sclerotic in 1 case,mixed in 7 cases and cystic-expansive in 2 cases.MRI findings (6 cases):the lesions were hypointense on T 1WI and hyperintense on T 2WI in 4 cases,mixed signal intensity on T 1WI and hyperintense on T 2WI in 1 case,isointense on T 1WI and mixed signal intensity on T 2WI in 1 case.Enhancement in most tumors was heterogenous.The cortical bone was destructed in 12 cases.Soft tissue masses were observed in all cases.Conclusion:NHL of bone usually involves either single bone or multiple bones.The pelvis,femur and vertebrae were the most frepuently involved.Extensive destructions and soft tissue masses are often seen.Diagnosis of NHL should be combined with clinical and pathological findings.
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