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《Radiologic Practice》 2005-02
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Investigation of Multi-Slice Spiral CT (MSCT) Perfusion Imaging before and after Transcatheter Arterial Embolization (TAE) in VX2 Soft-Tissue Tumor of Rabbit

ZHANG Jing-feng,WANG Ren-fa,WU Jing,et al.Department of Radiology,Tongji Hospital,Tongji Medical College,Huazhong University of Science & Technology,Wuhan 430030,P.R.China  
Objective:To investigate the value of MSCT perfusion imaging on monitoring the therapeutic effects after TAE in VX2 soft-tissue tumors of rabbit.Methods:12 New Zealand white rabbits which were implanted VX2 tumor in the single proximal thigh were performed CT plain scan and perfusion scan before and after TAE respectively,then the functional maps and perfusion parameters including blood flow (BF) and permeability surface (PS) of tumor tissues were calculated and analyzed. The changes of blood perfusion in tumor tissues were observed and compared with pathological fin- dings. Results:All the values of BF and PS in VX2 soft-tissue tumors were obviously higher than those in the normal muscular tissues and those after TAE.Conclusion:MSCT perfusion imaging is an accurate, convenient and relatively safe functional imaging technique which can give a quantitative assessment of blood perfusion in soft-tissue tumors and monitor the the-rapeutic effects of TAE.
【CateGory Index】: R738
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