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《Radiologic Practice》 2006-05
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Clinical Study of Diffusion Weighted Imaging in Brain Tumors and Peri-tumoral Region

MAI Xiao-li,CHU Cheng-feng,QIN Wei,et al.Department of Radiology,Zhongda Hospital,Southeast University,Nanjing 210009,P.R.China  
Objective:To investigate the value of diffusion weighted imaging(DWI) in the diagnosis and differential diagnosis of brain tumors.Methods:Thirty-five patients with surgery and pathology proven intracranial tumor were recruited.There were astrocytoma(n=16),brain metastases(n=12) and benign meningioma(n=7).Routine MRI plain scanning,with contrast enhancement and DWI were performed.On DWI images,signal value of enhanced region of tumors,as well as their adjacent/distant peri-tumoral areas and normal white matter were measured.ADC values and their statistical differences were calculated.Results:For the mean ADC value,there were significant difference between meningioma and astrocytoma or metastases(P0.05).ADC value in high grade astrocytoma is significantly lower than that of low grade astrocytoma(P0.05).For the ADC value of peri-tumoral region adjacent to astrocytoma,significant difference was displayed when compared with that of meningioma or metastases (P0.05).There was no significant difference in the distant peri-tumoral region of these 3 kinds of tumor(P0.05).Statistically significant difference existed between the ADC values of lesion and normal control region(P0.05).Conclusion:Evaluation of ADC value of brain tumors,especially adjacent peri-tumoral region,might be useful in the diagnosis and differential diagnosis of brain tumors as well as in the delineation of tumor border.
【CateGory Index】: R739.41
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